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Front page of My Duke Research

Studies

Children with atrioventricular septal defect (CHSS Cohort)

(MICA) Mechanistic Study of Inspiratory Training in Childhood Asthma

402-C-124 (Study for Healthy Volunteers)

A Randomized Phase II Study of Systemic Chemotherapy with or without Hai Fudr/Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma

A window of opportunity study of Patritumab Deruxtecan in patients with brain metastases

A022104 (JANUS): Locally Advanced Rectal Cancer

A031801: Advanced Renal Cell Carcinoma with Bone Metastasis

A052101: Mantle Cell Lymphoma

A081801 (Lung Cancer)

A082101 Sarcomatoid Mesothelioma Stage 1-3

A211901 Rural Cancer Survivors Who Smoke

AAVIATE - RGX-314-2102 (Age-Related Macular Degeneration)

ABBV-400 for Advanced Solid Tumors

ABBV-400 in Select Advanced Solid Tumor Indications

ABBV-453 for Relapsed or Refractory Multiple Myeloma

Abdominal Wall Transplant

AbelZeta_CTIL051 (Non-Small Cell Lung Cancer)

Ablative Radiotherapy in Metastatic Disease Registry

Adaptive PET II for Reproductive and Digestive Cancer

ADRC Clinical Cohort (Alzheimer's Disease)

Adults with Poorly Controlled Asthma

AFT-50 EndoMAP Targeted Agents and/or Immunotherapy with Atezolizumab for Endometrial Cancer

AGCT1531 (Children and Adults with Germ Cell Tumors)

ALADDIN (Aging and Memory Study)

ALKOVE-1 (Non-Small Cell Lung Cancer)

Alliance A151216: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

AMG 509 in patients with mCRPC (Prostate Cancer)

AMG 510 in Advanced Solid Tumors With KRAS p.G12C Mutation

Amgen 20190341

AML Remote Monitoring (Acute Myeloid Leukemia)

Antibiotic Prophylaxis in Rhinoplasty (Nasal Surgery)

APEC1621 Pediatric MATCH Study (Tumor Genetics)

APOLLO (Kidney Transplant)

APOLLO - Mitral Valve Regurgitation

ARC-21 (Gastrointestinal Cancer)

ARISE II (Ascending Aorta Repair)

ARTACUS (Skin Cancers in Organ Transplant Recipients)

ASCENT-05 for Triple Negative Breast Cancer with Residual Disease after Surgery

Astellas 2138 (Gastroesophageal Junction and Pancreatic Cancer)

ATARA_ALLELE_PTLD (Post-Transplant Lymphoproliferative Disease)

ATMOSPHERE (Macular Degeneration)

ATS22 (Amblyopia in Children)

Autogene Cevumeran plus Atezolizumab and mFolfirinox vs mFolfirinox alone (Pancreatic Cancer)

AZ NATRON - D3254C00001 (Hypereosinophilic Syndrome)

Baby Steps III (Smoking Cessation for Pregnant Women)

BabySTEPS2: Retinopathy in Toddlers Born Prematurely

Basket study of MK-4280A in select solid tumors (Cutaneous Squamous Cell Carcinoma)

BBI: TP-3654 in Patients with Myelofibrosis

Behring TAP Trial (Traumatic Injuries with Bleeding)

BGB-3245+Panitumumab in Advanced/Metastatic RAS mutant CRC & Pancreatic Ductal Cancers (MapKure)

BGBC016 STK11 NSCLC (Non-Small Cell Lung Cancer)

BI 1479-0001 HER2

Biobanking for OVCA (Ovarian Cancer)

Biorepository of Patients with Hidradenitis Suppurativa (HS)

BioSight-Eye and Tissue Bank, Registry and Repository

BMS CA125-1008 (Metastatic Castration Resistant Prostate Cancer)

Brain Imaging Research Participant Registry

Breast cancer blood/tissue repository and database

Breast Pre Cancer Atlas

BT015 Safety and Effectiveness of Exablate to Mediate Blood-Brain Barrier Disruption (Glioblastoma)

Cambria 1 for ER+/HER2- Early Stage Breast Cancer after Surgery

CardioTTRansform-OLE (Cardiac Amyloidosis)

CARS (Cardiac Amyloidosis Registry)

Catapult: Ph1a/b CAP-100 (Chronic Lymphocytic Leukemia)

CB-011 CRISPR Allogeneic Anti-BCMA CART in patients with R/R MM (Multiple Myeloma)

Celgene: GC-LTFU-001 (Multiple Myeloma)

Celgene: Ph3, Multi, Open, Comparing IberDd vs DVd in Subjects w/ RRMM (Multiple Myeloma)

Cell Transplantation for Drug-Resistant Epilepsy (NTE-001)

CG0070 in NMIBC Unresponsive to BCG - BOND-003 (Bladder Cancer)

CHAMP (Prostate Cancer)

Children with Tricuspid Atresia (CHSS Cohort)

Chronic Pain Research Volunteer Database

Cleft Lip

CleftKit and ACCQUIREnet Multisite (Cleft Lip)

Color Study (High-Risk Breast Lesions)

Communication After Right Brain Stroke

Compass CTX-471 (Advanced or Metastatic Cancer)

COMPASS HER2+ Breast with Residual Disease (A011801)

Compassion S3 for Transcatheter Heart Valve Placement in Adults and Children

COMPOSE Study (Neuroendocrine Tumors)

CONNECT 1903 - Larotrectinib for Children with Newly-Diagnosed HGG with NTRK Fusion

CONSYDER (Breast Cancer)

Continuous glucose monitoring for steroid induced hyperglycemia in breast cancer patients

Coping Together-2 (Cancer Support)

COVID-19 vaccine responses in PIDD subjects

CROWN Study (Breast Cancer)

CRSP-ONC-005 (Solid Tumors)

Cryocompression to Reduce Neuropathy Caused by Chemotherapy

CRYPTICS (Cardiopulmonary Bypass Surgery)

CSF Biobanking Protocol (Cancer with Spread to the Leptomeninges)

CTC - Immune Based Biomarkers (Kidney & Bladder Cancer)

CTSN PACES (A-Fib)

CTSN PRIMARY Trial (Mitral Valve Regurgitation)

D2C7 + Anti-CD40 for Malignant Glioma

da Vinci SP Surgical System vs. Open Surgery in Nipple-Sparing Mastectomy

Dabrafenib + Trametinib in Patients w/rare BRAF V600E Mutated Solid Tumor (CDRB436IIC01)

Dapansutrile Plus Pembrolizumab in Melanoma (DREAM)

Database/Repository for Abdominal Organ Transplant Recipients

Database/Repository for Cardiac Tissue and Related Specimens

DEPTH Trial (Emphysema in People Living with HIV)

Dermatology Future Research Participant Database

DSP: Phase 1/2 DSP-5336 in Acute Leukemia

Duke Behavioral Health & Technology Lab Data Repository (Volunteer Registry)

Duke Clinical Vaccine Unit Volunteer Registry

Duke COVID-19 Shared Repository

Duke Gastric and Gastroesophageal Junction Cancer Patient Registry

Duke Health and Exercise Research Trials Registry

Duke Health Research Volunteer Registry

Duke Lupus Registry

Duke Surgery Biorepository

EA2222 (Colorectal Cancer with Liver Metasases)

EA6192: Advanced Melanoma (PET-Stop)

Early Detection of Lung Cancer based on small RNA signatures

EAY191-A3 (RAS-Mutant Cancers)

EAY191-S3 Advanced non-breast solid tumors with AKT-alterations

ECOG-ACRIN EA4151 (Mantle Cell Lymphoma)

Effect of Corticosteroid Injections on Blood Glucose (Shoulder, Knee, or Hip Joint Pain)

ESR1 peptides vaccine study (Breast Cancer)

Ethicon Pelvic Mesh PMCF Registry

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

Expand URO (Genitourinary Cancers that Require Surgery)

FEATURES OF PRIMARY AND ADAPTIVE IMMUNOTHERAPY RESISTANCE IN MICROSATELLITE INSTABLE CANCERS

FlexED (Early Intervention for Eating Disorders)

GE43220 (Age-Related Macular Degeneration)

Generic Infection Protocol (MESSI)

Genetic Study for SCD and CHD (Heart Disease)

GOG-3068 HIPEC (Hyperthermic Ovarian Cancer Treatment)

GOG-3078 Immunogen IMGN853-0421 (Ovarian and Fallopian Tube Cancers)

GOG-3083 XPORT-EC-042 SELINEXOR IN MAINTENANCE THERAPY FOR ADVANCED ENDOMETRIAL CANCER

Gore TAMBE for Thoracoabdominal Anuerysms

GR43828 (Intravitreal Injections for Diabetic Macular Edema)

GRACE Study (Sickle Cell Disease Pain)

GRN163L vs BAT in MF (Myelofibrosis)

Hand transplantation

HBM Database Repository (HIV)

HEAD START 4 PROTOCOL (Pediatric Brain Cancer)

Healthy Volunteer Blood Draw Study

Hepatic Artery Chemotherapy for Patients with Localized Pancreas Cancer

HIBISCUS Study 4202-HEM-301 (Sickle Cell Disease)

HOBIT (Traumatic Brain Injury)

Hyperpolarized 129Xe MRI for Lung Function (Lung Disease & Healthy Volunteers)

I7P-MC-DSAF (Hidradenitis Suppurativa)

iACT for eating disorders in Type 1 Diabetes

ICU Biorepository

IIT: Ph2 Home Care Study Autologous Hematopoietic Stem Cell Transplantation

iMIND Research Study

IMPACt-LBP (Lower Back Pain)

Improving Cardiovascular Disease Risk for Young Adult Cancer Survivors

Insomnia PTSD

Inspiratory Muscle Training in LOPD (Pompe Disease)

Intraoperative OCT Guidance of Intraocular Surgery (Imaging of the Eye)

IRAD: Registry for Acute Aortic Dissection

Ironman Registry (Prostate Cancer)

It MATTERS - The Erectile Restoration Registry

IXT7 (Intermittent Exotropia in Children)

JUPITER 4.0 (Medial Patellofemoral Ligament Reconstruction)

K36 _KTX-MMSET-001_ Ph1 KTX-1001 Oral, FIC, MMSET Cat Inhib in Pts w/ RRMM (Multiple Myeloma)

Karyopharm: Ph1b/2 Selinexor with backbone tx (Multiple Myeloma)

Ketogenic Diet with Standard Treatment for Newly Diagnosed GBM (Glioblastoma)

KPG-818 (Blood, Bone Marrow, and Lymph Node Cancers)

KPI-012

Kura Oncology Ph1/2A KO-539 in R/R AML

LANCE Trial (Ovarian Cancer)

LBL-007+ Tislelizumab w/Bevacizumab vs. Bevacizumab and capecitabine in CRC (Colorectal Cancer)

Leukapheresis Protocol

Lima: SMR Stemless Reverse vs SMR Reverse Shoulder System (Shoulder Joint Replacement)

Loxo III: Trial of Fixed Pirtobrutinib + Vene and Rituximab in CLL/SLL (Leukemia)

Lung Health Cohort (Healthy Volunteers)

Lyell LYL845 (Solid Tumors)

M23-698 (Hidradenitis Suppurativa)

MADRA Registry (Women with Autoimmune & Rheumatologic Diseases)

Magnetic Resonance Imaging (MRI) for Assessing Spinal Metastases

MANTRA (Heart Valve Disease)

MB-CART2019.1 DLBCL (Diffuse Large B Cell Lymphoma)

Medtronic Cardiac Device Registry

Medtronic PAN Registry (Urological and Digestive Disorders)

Megestrol acetate compared with megestrol acetate and metformin to prevent endometrial cancer

Melanoma Biorepository

MEM-288 (solid tumors)

Menopause in Women with Sickle Cell Disease

Merck LEAP-009 (Head and neck squamous cell carcinoma)

Merck Prostate 365 - Combination therapies for mCRPC (Prostate Cancer)

Merck V940-004: mRNA based vaccine (V940) + Pembrolizumab for Renal Cell Carcinoma

Mind to Quit Trial (Smoking Cessation)

MISO-STIM (Misophonia)

MoTrPAC: An Exercise Study to Improve Health and Prevent Disease

MOUNTAINEER-03 (Colorectal Cancer)

MRI following Stereotactic Radiosurgery for Brain Metastases

MRI Study of Aging and the Brain

Multi-Kinase Inhibitor with or without Atezolizumab in Previously Treated Liver Cancer

Muscle progenitor cell VEGF receptor signaling in patients with peripheral arterial disease

NAFLD in HIV Database (HIV & Non-Alcholic Fatty Liver Disease)

Nasal tissue analysis for COVID19

National Spina Bifida Patient Registry

NC Registry for Brain Health in Aging

NDPH biomarker study (New Daily Persistent Headache)

Neoadjuvant Daromun + Surgery (Melanoma)

Neoimmunetech_NT-I7_Ph1b_R/R_LBCL (Large B Cell Lymphoma)

Neurocognitive Symptoms in Hyperparathyroidism

Neurostimulation versus therapy for problems with emotions

Nivolumab + Ipilimumab Comparison Study (Melanoma)

Normative qVOMS (Study Using Healthy Volunteers to Improve Concussion Diagnostics)

NRG-BR009 OFSET (Breast Cancer)

NRG-CC008: Ovarian Cancer

NRG-GI008 Colon Cancer

NRG-GU008 Prostate Cancer

NRG-GU009 (Prostate Cancer)

NRG-GY024 (Vulvar Cancer)

NRG-GY025: NRG-GY025, A Randomized Phase II Trial of Nivolumab and Ipilimumab compared to Nivolumab Monotherapy in Patients with Deficient Mismatch Repair System Recurrent Endometrial Carcinoma --Safety Lead-in Portion (NCT # 05112601)

NRG-GY026: Stage 1-IV Endometrial Serous Carcinoma or Carcinosarcoma

OASIS Study: Comparison of 3 Different Interventions for Shoulder Instability

OBERON (Chronic Obstructive Pulmonary Disease)

OCU410-101 (Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration)

OCU410ST-101 (Stargardt Disease)

OncoCHAT (Advanced Solid Cancer)

ONE TEAM Study (Managing Heart Health During Cancer Treatment)

OPAL R01 (Chronic Pain Imaging Study)

Oxbryta Product Registry (Sickle Cell Disease)

P-RAD Extension Trial (Breast Cancer)

Parasol - 81201887MDG2001 (Age-Related Macular Degeneration)

Perioperative dostarlimab vs standard of care for resectable colon cancer (219606) (AZUR)

PET-CT for Dose Reduced Radiotherapy in HPV-positive Oral Cancer

Ph I/II of GOS in acute GVHD (Stem Cell Transplantation)

Ph2 INBRX-109 (Unresectable or Metastatic Conventional Chondrosarcoma)

Phase 3 Randomized Double-Blind Study of Abemaciclib versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

Phase 3 Study of Adjuvant V940 and Pembrolizumab in Resected Melanoma

PHOENIX (Geographic Atrophy)

pING-HER3 Vaccine for Cancer

Pneumothorax Ultraound in Humans with Clarius

PNOC022: A Combination Therapy Trial for Diffuse Midline Glioma

POLARIS (Stargardt Disease Type 1)

POLARIS 2022-001 (Leiomyosarcoma)

PRECIDENTD (Type 2 Diabetes)

PRECISE Study (Ovarian Cancer)

Precision Medicine mCRC (Liver Cancer)

Predicting Transitions from Acute to Chronic Low Back Pain

PREMIER Trial (Uterovaginal Prolapse)

PREVENTABLE (Dementia Prevention in Older Adults)

PROCOVAXED (COVID-19)

Project HOPE 1000 (Better Understanding Pregnancy)

Project HOPES (Smoking Cessation for Cancer Survivors)

PROPEL Study (Lung Transplant)

Propella: Intramuscular abiraterone decanoate for metastatic prostate cancer

Prothena: Ph3 (Amyloidosis)

PROVE-HCC: A study for People with Liver Cancer

Pulmonary Medicine - Healthy Volunteer Registry

Pulmonary Medicine LDVDR (Lung and Breathing Disorder Research Registry)

PuMP: Oncolytic HSV1 MVR-C5252 in Patients with rHGG (Recurrent Glioma)

QOL Ped Intestinal Failure (Short Bowel Syndrome)

Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder Instability

Randomized Ph.2 Trial for Lerapolturev (PVSRIPO) in rGBM (Recurrent Glioblastoma)

Rare Breast Tumor Registry

Regional Anesthesia following Pediatric Cardiac Surgery

REPAIR-MR (Primary Mitral Regurgitation)

Replimune (Melanoma and Other Skin Cancers)

RESTORE

RGX-314-3101 (Macular Degeneration)

ROCC Trial (Cervical Cancer)

ROCKaspire

ROCKET-ASTRO (Atopic Dermatitis/Eczema)

Role of Hormones in Hidradenitis Suppurativa (HS) and Other Skin Diseases

ROMA Women (Coronary Artery Bypass Surgery)

S1925: Phase III Study of Newly Diagnosed Asymptomatic High-Risk Patents with CLL/SLL

S2114: Therapy Following CAR-T (Diffuse Large B-cell Lymphoma or Grade IIIB Follicular Lymphoma)

S2200: Advanced Papillary Renal Cell Carcinoma (PAPMET2)

S2302 Stage IV or Recurrent Non-Small Cell Lung Cancer

Sandcat GR44278 (Uveitic Macular Edema)

SBR Bariatric Access Protocol (Chronic Pain and Obesity)

Sc2i TDAP (Surgery)

SCD-CARRE (Sickle Cell Disease)

SCOPE-Leukemia

SEAGEN InnovaTV207 (Squamous Cell Cancer of the Head and Neck)

SEER-2 (Neurotrophic Keratopathy)

SGT-610-01 (Gorlin Syndrome/Facial Basal Cell Carcinoma)

SICKLE-FIT Study (Exercise for Adults with SCD)

Silence: SLN124 in patients with Polycythemia Vera

SLIVR

SMX22-002: Locally Advanced or Metastatic ER+/HER2- Breast Cancer with an ESR1 Mutation

SRS and Olaparaib followed by Durvalumab in Breast Cancer with Brain Metastases (SOLARA)

STaR Study for Multiple Ligament Knee Injuries (MLKI)

Steatosis in HIV Study

Stellar-002: XL-092 (Kidney, Bladder, and Prostate Cancer)

STRIVE #2 (COVID-19)

Study drug QTX3034 for patients with KRAS G12D solid tumors (QTX3034-001)

Study drug RO7589831 for MSI/dMMR solid tumors (BP44474)

Summit Ph2 CGT9486 in Nonadvanced Systemic Mastocytosis

SWOG S2015: Comparing Resection Options in Melanoma Removal

Synthekine STK-012 (Solid Tumors)

T1D-Linked: Registry of Patients with Type 1 Diabetes

Tailored Axillary Surgery in Node-Positive Breast Cancer

TAK-279-3002 (Moderate-to-Severe Plaque Psoriasis)

TBCRC 047: InCITe (Breast Cancer)

The STOP-HER2 Trial: Outcomes in Patients with HER2+ Metastatic Breast Cancer

The TENDER Study (Dextenza Insert in Children)

Thoraflex EXTEND (Stress Management for People with Heart Disease)

Tissue & Data Acquisition (Gynecologic Cancer)

TITAN (Aortic Aneurysm)

TMIST Mammography Study (Breast Cancer Screening)

TOP 2101 - Metastatic Non-Small Cell Lung Cancer

TPE in Heparin-Induced Thrombocytopenia (HIT)

Treatments for Patients with Resipiratory Infections/STRIVE (COVID-19)

TRIOMPHE Study (Aortic Arch Disease)

Tyra SURF-301: Phase 1/2 study for patients with urothelial carcinoma and an FGFR3 alteration

U01 Endometrial Basis for RIF and PL (Infertility)

UNC ACL PTOA: A Study of Recovery after Anterior Cruciate Ligament (ACL) Reconstruction

Understanding Young Adult Male Cancer Survivors' Sexual Health

Uni-Rare (Retinal Dystrophy)

VCA Biorepository & Database Study (Body Tissue Transplantation)

Videofluoroscopic Swallowing and Ultrasound

ViSPad Supportive Care Study for Brain Tumor Patients

Vivo SBIR (Prediabetes)

VOC in Lung Transplant Rejection

Well-Being ABCs (Well-Being After Breast Surgery)

X-PACT Immunolight (Breast Cancer, Head & Neck Cancer, Melanoma, and Sarcoma)

Xencor_XmAb819-01 (Clear Cell Renal Cell Carcinoma)

Xenon MRI in ILD (Lung Disease & Healthy Volunteers)

XVIVO PRESERVE (Heart Transplantation)

Zion (Solid Tumors)

Study Results

Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE)

CTSU ECOG E5508 Study for Non-Small Cell Lung Cancer

DASH Diet in African Americans with Chronic Kidney Disease Focus Group Study

Durham Initiative for Stomach Health (DISH)

Hearing Screening in Primary Care Clinics

How the Effect of Concussions on Responsiveness Increases Risk of Future Injury

Multi-Ligament Knee Injury Repair

Patient Preferences on Treatment Decisions for Shoulder Dislocations

SWOG S1203 Study for Acute Myeloid Leukemia

The INSPIRE Study: Comparing Options to Manage Chronic Pain

Why Student Athletes See the Doctor

Events

Angels Among Us 5K & Walk of HOPE

Cancer Patient Caregiver Support Group (Virtual Event)

Collaborative Action for America’s Health: Short- and Long-Term Strategies Across Public Health, Health Systems, and Social Services

Duke Caregiver Community Event

Examples From the Field: Communities and Researchers Advocating for Birth Justice to Improve Maternal Health Outcomes and Promote Health Equity

Lunch & Learn Kidney Health Screening

Test event for content entry training