IIR-2023-1274 (Dry Eye from Sjogren's Syndrome)

Purpose of this Study

We are doing this study to learn more about how different factors affect people with two types of dry eye conditions: Sjögren's dry eye (SjD) and non-Sjögren's dry eye. Specifically, we want to know how neurotrophic keratitis (a condition where the cornea loses sensation) versus the severity of tear film and eye surface issues impact the structure and function of the cornea (the clear front part of the eye). We also want to find out if having dry eyes leads to less feeling in the cornea, and if this reduced feeling is linked to eye pain or pain in other parts of the body.

Who Can Participate?

Eligibility

Adults ages 18+ who:
  • Are diagnosed with dry eye
  • Are diagnosed with Sjögren's Syndrome
  • Have no history of glaucoma surgery
For more information, contact the study team at DEC_ResearchAdmin@dm.duke.edu.

Age Range

18-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No

What is Involved?

Description

If you choose to join this study, you will come in for a single visit to have the following procedures:
  • An eye exam
  • Imaging scans of the eye
  • Questionnaires

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

No

Spanish Materials Available

No

Study Details

Full Title

Role of Neurotrophic Keratitis versus Severity of Tear Film and Ocular Surface Parameters in Determining the Differences in Corneal Structure and Function in Patients with Sjögren's vs. non-Sjögren's Dry Eye - IIR-2023-1274

Principal Investigator

Amol
Sura

Protocol Number

PRO00117774

Phase

N/A

Enrollment Status

Pending Open to Enrollment