SLIVR

Purpose of this Study

We are doing this study to find out if a new type of assessment works well for middle-aged and older adults with sickle cell disease (SCD). We want to see if this assessment is useful in detecting changes in health. We hope the assessment can provide useful information to help improve the quality of life for adults with sickle cell disease.

Who Can Participate?

Eligibility

Adults ages 40+ who are diagnosed with SCD.

For more information about who can be in this study, please contact the study team at stephanie.padrick@duke.edu.

Age Range

40-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No

What is Involved?

If you choose to join this study, you will visit our clinic 1-4 times a year for up to 10 years to have the study assessments done. These assessments will take about an hour to finish and will include the following:<ul>
<li>Walking tests</li>
<li>Balance tests</li>
<li>Upper-body strength testing and measurement</li>
<li>Chair stands</li>
<li>Blood draws and urine collections</li>
<li>Surveys</li></ul>
During these visits, we will give you an activity monitor to keep track of your physical activity for one week after each visit. This activity monitor fits around your wrist like a watch.

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Focused Geriatric Assessment, Frailty, and Biomarkers to Determine Physiologic Resilience in Older Adults with Sickle Cell Disease (FGA-SCD)

Principal Investigator

Charity
Oyedeji

Protocol Number

PRO00100358

Phase

N/A

Enrollment Status

Open to Enrollment