Hyperpolarized 129Xe MRI for Lung Function (Lung Disease & Healthy Volunteers)

Purpose of this Study

If you agree to be in the study, you will have 1 study visit that will last about 4 hours.
The visit will include asking questions about your medical history, vital signs, pulmonary function tests (PFTs) and an MRI (magnetic resonance image) of the chest with inhaled Xenon gas.
Someone from the study team will contact you about 24 hours after your study visit.

Who Can Participate?

Eligibility

Adult patients with lung disease and healthy volunteers

Age Range

18-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

We are doing this study to learn whether magnetic resonance images of the lung using inhaled xenon gas (Xe MRIs) can show any difference between healthy people, those at risk of developing lung disease, and those with lung disease. We also want to test better ways to do MRI scans and improve their quality

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects with Pulmonary Disease

Principal Investigator

Joseph
Mammarappallil

Protocol Number

PRO00025110

NCT ID

NCT01280994

Phase

I

Enrollment Status

Open to Enrollment