Purpose of this Study
If you agree to be in the study, you will have 1 study visit that will last about 4 hours.
The visit will include asking questions about your medical history, vital signs, pulmonary function tests (PFTs) and an MRI (magnetic resonance image) of the chest with inhaled Xenon gas.
Someone from the study team will contact you about 24 hours after your study visit.
The visit will include asking questions about your medical history, vital signs, pulmonary function tests (PFTs) and an MRI (magnetic resonance image) of the chest with inhaled Xenon gas.
Someone from the study team will contact you about 24 hours after your study visit.
Who Can Participate?
Eligibility
Adult patients with lung disease and healthy volunteers
Age Range
18-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
We are doing this study to learn whether magnetic resonance images of the lung using inhaled xenon gas (Xe MRIs) can show any difference between healthy people, those at risk of developing lung disease, and those with lung disease. We also want to test better ways to do MRI scans and improve their quality
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects with Pulmonary Disease
Principal Investigator
Joseph
Mammarappallil
Protocol Number
PRO00025110
NCT ID
NCT01280994
Phase
I
Enrollment Status
Open to Enrollment