Predictors in SCD (Sickle Cell Disease Pain)

Purpose of this Study

We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.

Who Can Participate?

Eligibility

Adults and children ages 15-40 who:

Are diagnosed with sickle cell disease
Have used a strong pain medication, like morphine or oxycodone, in the past 12 months to treat a sickle cell pain crisis either at home or in the hospital
Are not pregnant
Have never received gene therapy or a bone marrow transplant

For more information about who can be in this study, please contact the study team at omowunmi.olaleye@duke.edu.

What is Involved?

Description

If you choose to join this study, you will:

Fill out surveys about your health, mood, and pain
Undergo standard pain testing that uses different sensations

One test involves pressure, and it uses a tool that pushes firmly against your skin. Another test involves heat, and it uses a tool that slowly becomes warm. The final test sees how you respond to "pin pricks," and it uses a tool with a sharp end like a safety pin. The pain tests are important for showing us how your brain "sees" pain. They may be slightly uncomfortable, but they are safe, they cause no damage, and you can stop the tests whenever you want.

Study Details

Full Title

Predictors of Pain Severity and Pain-Related Outcomes in Individuals with Sickle Cell Disease

Principal Investigator

Martha

Kenney

Protocol Number

PRO00112024

NCT ID

NCT06139510

Phase

N/A

Enrollment Status

Open to Enrollment

ClinicalTrials.gov