Purpose of this Study
This study includes up to three sessions that take about 5 to 6 hours in total. These sessions can happen all on the same day or be spread out over two months. People who join will first go through a screening and sign consent forms. They will then have an MRI scan and do head-tracking tasks using two different systems - one regular and one that uses computer vision.
The study also includes finding the TMS motor threshold, which means using a small magnetic pulse to make a finger twitch. Participants will also receive sham TMS, which feels like real TMS but does not affect the brain, over a part of the brain called the prefrontal cortex.
This study is testing a new, non-invasive system that does not need tracking tools on the head. It is made for research and does not involve any medicine or random group assignments.
Who Can Participate?
Eligibility
To join this study, people must be 18 years old or older. They need to be able to understand the study and agree to take part by signing a consent form. They must also be okay with being recorded by video cameras during the study.
Participants must be able to have an MRI scan, which means they cannot have anything in or on their body that would make it unsafe. They must not have any serious mental or brain-related health problems, including a history of seizures or taking medicines that could make seizures more likely.
Age Range
18-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Looking for Healthy Participants
Yes
What is Involved?
Description
This study is testing a new way to guide a brain stimulation tool called TMS by using a camera to track a person’s head. The goal is to do this without needing special headgear. Researchers hope this new method will make the treatment more comfortable and easier for people. They also want to see if it helps aim the tool more accurately, which could improve how well the treatment works.
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Computer vision navigation for magnetic brain stimulation
Principal Investigator
Angel
Peterchev
Protocol Number
PRO00119192
Phase
Pilot
Enrollment Status
Pending Open to Enrollment