Purpose of this Study
We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families.
Some conditions that we are looking at are:
-Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) such as hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy
-Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast), such as long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, short QT syndrome
-Sudden cardiac arrest or unexplained sudden death (heart stops suddenly), including sudden infant death syndrome (SIDS)
Some conditions that we are looking at are:
-Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) such as hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy
-Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast), such as long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, short QT syndrome
-Sudden cardiac arrest or unexplained sudden death (heart stops suddenly), including sudden infant death syndrome (SIDS)
Who Can Participate?
Eligibility
- Infants
- Children
- Adults, 40 and under
- Children
- Adults, 40 and under
Age Range
0-100
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
If you choose to join this study, you will:
-Give a blood sample (must be able to travel to Duke for this)
-We may also ask family members to join the study to learn more about a disease running in the family.
For more information about who can be in this study, please contact the study team at landstromlab@duke.edu.
-Give a blood sample (must be able to travel to Duke for this)
-We may also ask family members to join the study to learn more about a disease running in the family.
For more information about who can be in this study, please contact the study team at landstromlab@duke.edu.
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
No
Spanish Materials Available
Yes
Study Details
Full Title
The Genetic and Molecular Basis of Sudden Cardiac Death-Predisposing Diseases and Congenital Heart Conditions
Principal Investigator
Andrew
Landstrom
Protocol Number
PRO00094341
Phase
N/A
Enrollment Status
OPEN TO ACCRUAL