Genetic Study for SCD and CHD (Heart Disease)

Purpose of this Study

We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families.

Some conditions that we are looking at are:<ul>
<li>Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) like hypertrophic cardiomyopathy, dilated cardiomyopathy, or arrhythmogenic right ventricular cardiomyopathy</li>
<li>Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast) like long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or short QT syndrome</li>
<li>Sudden cardiac arrest or unexplained sudden death (heart stops suddenly), including sudden infant death syndrome (SIDS)</li></ul>

Who Can Participate?

Eligibility

Children and adults who are younger than 40 years old.

For more information about who can be in this study, please contact the study team at landstromlab@duke.edu.

Age Range

0-100

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

If you choose to join this study, you will:<ul>
<li>Give a blood sample (must be able to travel to Duke for this)</li>
<li>We may also ask family members to join the study to learn more about a disease running in the family</li></ul>

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

No

Spanish Materials Available

Yes

Study Details

Full Title

The Genetic and Molecular Basis of Sudden Cardiac Death-Predisposing Diseases and Congenital Heart Conditions

Principal Investigator

Andrew
Landstrom

Protocol Number

PRO00094341

Phase

N/A

Enrollment Status

Open to Enrollment