ADRC Clinical Cohort (Alzheimer's Disease)

Purpose of this Study

We are doing this study to learn more about Alzheimer's disease and other illnesses of aging (e.g., dementia, mild cognitive impairment [MCI], or other cognition disorders).

Who Can Participate?

Eligibility

Adults ages 45-80 who:
  • Are be able to read at a 6th grade level
  • Are willing to have an MRI scan and a lumbar puncture or PET scan
  • Have a study partner
For more information about who can be in this study, please contact the study team at ADRC@duke.edu or 919-660-2340.

Age Range

25-80

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

Description

This study will ask that you have a study partner. This is usually a family member that can answer questions about your day-to-day activities. If you choose to join this study, you will:
  • Complete 3 study visits in 60 days and then yearly visits after that
  • Do brain and thinking tests
  • Have physical exams
  • Do memory tests
  • Complete medical and family history surveys
  • Get a brain MRI (image)
  • Have a lumbar puncture (spinal tap) or PET Scan
At your yearly follow-up visit, you will:
  • Do memory testing
  • Have a blood test

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Duke Alzheimer's Disease Center Clinical Cohort (Duke as Single IRB of Record)

Principal Investigator

Heather
Whitson

Protocol Number

PRO00103958

NCT ID

NCT06703541

Phase

N/A

Enrollment Status

Open to Enrollment