Purpose of this Study
We are doing this study to learn more about Alzheimer's disease and other illnesses of aging (e.g., dementia, mild cognitive impairment [MCI], or other cognition disorders).
Who Can Participate?
Eligibility
Adults, 45-80 who:
-Are be able to read at a 6th grade level
-Are willing to have an MRI scan and a lumbar puncture or PET scan
-Have a study partner
-Those that have a memory problem, or a family history of them, and those who do not
For more information about who can be in this study, please contact the study team at ADRC@duke.edu or 919-660-2340.
-Are be able to read at a 6th grade level
-Are willing to have an MRI scan and a lumbar puncture or PET scan
-Have a study partner
-Those that have a memory problem, or a family history of them, and those who do not
For more information about who can be in this study, please contact the study team at ADRC@duke.edu or 919-660-2340.
Age Range
25-80
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
This study will ask that you have a study partner. This is usually a family member that can answer questions about your day-to-day activities.
If you choose to join this study, you will:
-Complete 3 study visits in 60 days and then yearly visits after that
-Do brain and thinking tests
-Have physical exams
-Do memory tests
-Complete medical and family history surveys
-Get a brain MRI (image)
-Have a lumbar puncture (spinal tap) or PET Scan
At your yearly follow-up visit, you will:
-Do memory testing
-Have a blood test
If you choose to join this study, you will:
-Complete 3 study visits in 60 days and then yearly visits after that
-Do brain and thinking tests
-Have physical exams
-Do memory tests
-Complete medical and family history surveys
-Get a brain MRI (image)
-Have a lumbar puncture (spinal tap) or PET Scan
At your yearly follow-up visit, you will:
-Do memory testing
-Have a blood test
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Duke Alzheimer's Disease Center Clinical Cohort (Duke as Single IRB of Record)
Study Website
Principal Investigator
Heather
Whitson
Protocol Number
PRO00103958
Phase
N/A
Enrollment Status
OPEN TO ACCRUAL