Purpose of this Study
We are doing this study to help develop a tool that doctors can use to figure out who might be at risk for developing muscle spasticity after a stroke. Spasticity is abnormal muscle stiffening that can lower people's strength and ability to move well. We hope this tool can help doctors catch this problem early and start treatment sooner to make therapy more effective.
Who Can Participate?
Eligibility
Adults ages 21+ who:
- Either had their first stroke, or had a second stroke after having full recovery of their movement after the first stroke
- Have weakness or trouble moving on one side of the body, with scores on movement tests showing moderate to severe difficulty
- Were mostly independent before the stroke, with little to no disability that affected their daily life
Age Range
21-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No
What is Involved?
Description
If you choose to join this study, we will meet with you for physical exams and to check for muscle stiffness at the following time points:
- Between 2 and 7 days after your stroke
- About 30 days after your stroke (give or take 10 days)
- About 90 days after your stroke (give or take 2 weeks)
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Predicting Post Stroke Limb Spasticity
Principal Investigator
Wuwei
Feng
Protocol Number
PRO00103208
Phase
Pilot
Enrollment Status
Open to Enrollment