Clinical Trials Directory

445 clinical trials found.
Genitourinary Cancer

We are doing this study to compare two treatment options for PRCC. We want to know if adding an experimental drug called atezolimumab (the study drug) to the typical drug used in PRCC treatment, cabozantinib, can improve outcomes or extend survival time.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called DISC-3405 (the study drug) in adults with polycythemia vera (PV).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Surgery and Rehabilitation

We are doing this study to collect data and samples to store them for future research. We hope the data and samples will lead to improved treatment of patients who are seriously ill or have been injured.

Compensation: No
Ages: 18-90
Non-Oncology
Duke University Hospital
Immune System and Infections

This is a biosample collection study for people in the Surgical Critical Initiative Tissue and Data Acquisition Study If you join this study, you will: - Have blood drawn (an extra 2 teaspoons) at time of your injury or surgery, on Days 1, 3 and 7 after your injury or surgery, and weekly while you are in the hospital. We may also collect fluid or tissue from your wound and pictures of it We will also collect blood near time of surgery or if you get worse. We will also ask to use data collected under TDAP for analyses.

Compensation: No
Non-Oncology
Blood Disorders

We are doing this to see the effects of giving long-term red blood cell exchange transfusion to patients with sickle cell disease (SCD). We want to know if exchange blood transfusion may help with serious complications of SCD or reduce the chances of a new, serious problem happening.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called SGR-1505 (the study drug). We want to know how well this study drug specifically targets a protein related to your B-cell cancer.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to determine whether specialty palliative care or primary palliative care is the best way to improve the quality of life and experience of patients and their caregivers.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to find out if an investigational drug called RGN-259 Thymosin Beta 4 eye drops solution (the study drug) is a safe and effective option for the treatment of neurotrophic keratopathy.

Compensation: No
Non-Oncology