Clinical Trials Directory

We created this registry for people with rare breast tumors to help us learn more about them and how to better treat people in the future.

We are doing this study to find out if an experimental drug called ravulizumab (the study drug) is a safe and effective option to prevent or reduce the severity of delayed graft function after people with end-stage kidney disease (ESKD) get a kidney transplant.

The purpose of this study is to see how a treatment called TMS can help people move their arms better. TMS stands for transcranial magnetic stimulation. It uses magnets to help the brain work in a different way. TMS is already approved to help people with depression, and doctors have also looked at how it helps people after a stroke. But scientists still need to learn the best way to use it to help people recover.

If you join this study, you will have the surgery your doctor planned. You can choose to use the regular tool or be randomly picked to use either the regular tool or a new one. Blood will be taken three times (before, during, and after surgery). Doctors will also check your regular cancer visits for one year. The study does not add extra visits or tests.

If you decide to join this study, doctors will first check your medical history and the medicines you are taking to see if you can be part of it. If you qualify, you will have several tests, including: - A heart scan (CT or MRI) - An ultrasound of your heart - A full check-up, including your heart and brain if you had a stroke before - Blood tests to check things like salt levels, kidney and liver health, and heart function - A heart test called an ECG - A walking test to see how far you can walk in 6 minutes - A survey called the Kansas City Cardiomyopathy Questionnaire to learn how you feel Some visits may take a long time, up to 8 hours.

We are doing this study to find out if an experimental study drug called RP1 (the study drug) is a safe and effective option for people who have advanced melanoma. We want to know how the study drug works when it is combined with a cancer drug called nivolumab in comparison to several other standard treatments for advanced melanoma (nivolumab + relatlimab OR nivolumab alone OR pembrolizumab alone).

We are doing this study to find out if an experimental drug called RP2 (the study drug) is a safe and effective option for people who have uveal melanoma (melanoma in the eye). We want to know how well the study drug works when it is combined with a drug called nivolumab, and we will compare its outcomes to treatment with the drug combination of nivolumab + ipilimumab.

We are doing this study to find out if a drug called rosuvastatin (an FDA-approved medication for lowering cholesterol) can help reduce symptoms and extend the life expectancy of people with liver cirrhosis. Although rosuvastatin is an approved and commonly prescribed drug, it is not approved for the treatment of cirrhosis.