Clinical Trials Directory

433 clinical trials found.
Bones, Joints and Muscles

We are doing this study to understand how different factors, such as pain experiences and inflammation, may affect how acute back pain transitions to chronic back pain.

Compensation: Yes
Ages: 18-110
Non-Oncology
Kannapolis, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called iadademstat (the study drug). We want to know if the study drug is beneficial for people with R/R AML that have the FLT3 mutation when it is given in combination with gilteritinib.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to find out if an investigational implanted drug called Ocular Therapeutix Tyrosine Kinase Inhibitor Axitinib (the study drug) is a safe and effective option for people with nAMD.

Compensation: Yes
Ages: 50-110
Non-Oncology
Duke University Hospital
Heart and Circulation

If you agree to be in this study you will: - Have your aorta repaired with the Thoraflex Hybrid device - Have information collected from your medical record - Have study visits for up to 10 years after your aortic repair surgery (some may be completed via phone)

Compensation: No
Non-Oncology
Genitourinary Cancer

Compensation: No
Oncology
Heart and Circulation

We are doing this to compare the results of early surgical intervention to medical therapy. We want to know if there is a difference in outcomes for these treatment options. We also want to track the health and progress of people with a large ascending aortic aneurysm (a bulge in the aorta caused by weakening in the artery wall).

Compensation: No
Non-Oncology
Cancer Immunotherapy

We are doing this research study to learn about the safety and effectiveness of alirocumab (a cholesterol-lowering drug) when it is combined with cemiplimab (an immunotherapy drug) and preoperative chemotherapy in patients with stage 1B-3A non-small cell lung cancer (NSCLC) who will undergo surgery. This study is important because it might potentially improve outcomes for you and other future patients.

Compensation: No
Oncology
Gynecologic Cancer

We are doing this study to find out if an experimental drug called TORL-1-23 (the study drug) is a safe and effective option for women who have advanced ovarian cancer, primary peritoneal, or fallopian tube cancer.

Compensation: No
Ages: 18-110
Oncology
Duke Raleigh Hospital