Clinical Trials Directory

We are doing this study to find the most effective, safe dose of an experimental drug called zanzalintinib (the study drug). We want to know how well it works in combination with pembrolizumab when it is given to people who have recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

We are doing this study to find out what the safest and most effective dose of the study drug (ZN-A-1041) is when given alone or in combination with capecitabine.