Clinical Trials Directory

445 clinical trials found.
Immune System and Infections

We are doing this study to find out how common it is for people who have HIV to accumulate excess fat in the liver or develop steatotic liver disease.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
COVID-19

We are doing this study to find out if an investigational drug called abatacept (the study drug) is an effective option when it is given along with the current standard treatment for COVID-19.

Compensation: Yes
Ages: 18-100
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Pickett Road Research

We are doing this study to learn more about how environmental contaminants (e.g., "forever chemicals") can affect people's likelihood of developing liver disease.

Compensation: Yes
Ages: 40-75
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to see if the study drug, PT886, with or without chemotherapy and/or pembrolizumab, is a safe and effective option for gastric and pancreatic cancer. We are also trying to find the best dose of the study drug to use.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to see if the study drug, QTX3034, either with or without cetuximab, is safe and effective for treating KRAS G12D mutated cancer. We are also trying to find the best dose of QTX3034 to use.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called QTX3046 (the study drug) is a safe and effective option for KRAS G12D mutated cancer. We want to know how well it works on its own and in combination with a drug called cetuximab, and we are also trying to find the best dose of the study drug to use.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an investigational drug called RMC-9805 (the study drug) is a safe and effective option for treating KRAS G12D mutated cancer. We are also trying to figure out what dose of the study drug works best for most people.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called RO7589831 (the study drug) is a safe and effective option for cancers with solid tumors. We also want to find out what the best dose of the study drug is in this study.

Compensation: No
Oncology