Clinical Trials Directory

403 clinical trials found.
Skin Cancer - Melanoma

We are doing this study to find out how much skin should be removed from around a melanoma to lower the chances of the melanoma coming back. We don't have enough evidence to know exactly how much skin to remove around the melanoma to give people the best chance at a good outcome.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Cancer Immunotherapy

We are doing this study to find out if an experimental drug called STK-012 (the study drug) is a safe and effective treatment for different types of cancer.

Compensation: No
Oncology
Diabetes Mellitus

We are doing this study to help connect people with type 1 diabetes to research studies they may be eligible to join as participants.

Compensation: Yes
Ages: 16-50
Non-Oncology
Duke University Hospital, Other

We are doing this study to find out if radiation to the axillary (armpit) lymph nodes is equally effective and causes fewer side effects than surgical removal of the lymph nodes in patients with breast cancer.

Compensation: No
Ages: 18-110
Duke University Hospital
Sarcoma

We are doing this study to test how effectively a drug called emactuzumab works to reduce tumor size in people with tenosynovial giant cell tumors (TGCT).

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to found out if a study drug called tarlatamab is a safe and effective option for patients with extensive stage small cell lung cancer (ES SCLC). We will compare the outcomes of how people do when they get a regimen of the study combined with durvalumab versus a regimen of durvalumab on its own.

Compensation: No
Ages: 18-64
Oncology
Duke University Hospital, Duke Raleigh Hospital
Breast Cancer

We are doing this study to find out if avelumab is a safe and effective option for triple negative metastatic breast cancer when it is combined with different anti-cancer drugs.

Compensation: No
Ages: 18-89
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called TL-895 (the study drug) is a safe and effective option for people with indolent systemic mastocytosis.

Compensation: No
Oncology