Clinical Trials Directory
Study of Combo of Anti-LAG-3 & Anti-PD-1 Antibodies in Subjects with Advanced or Metastatic Melanoma
We are doing this study to find the most effective, safe dose of a combination of the drugs fianlimab and ceminplimab. We want to know if this combination is an option for people with melanoma. We will compare how well this drug combination works to the usual treatment of relatlimab and nivolumab, which has the brand name Opdualag®.
If you choose to join this study, you will:
- Get 2-6 cycles of Inotuzumab Ozagamicin, lasting 1 month per cycle
- Get Methotrexate on day one during cycle 1 and on day 28 of cycles 2, 4 and 6
- Get about 3-5 mL of blood collected prior to treatment and at three time points during cycle 1 and 4 time points during cycle 2
We are doing this study to compare 3 different computer applications that are designed to help doctors analyze liver images and understand what's happening in the liver. One application is made by the Bashir Lab at Duke University, and the other two are the "DL-based Liver Segmentation" and the "iLiverLab" applications made by Siemens Healthineers.
We are doing this study to find the most effective and safe dose of an experimental drug called LY3537982 (the study drug) for people who have NSCLC that has KRAS G12C mutations.
We are doing this study to evaluate whether exercise training following allogeneic stem cell transplant can improve physical function, cognitive function, mental health, social support, and quality of life.
We are doing this study to find out how much skin should be removed from around a melanoma to lower the chances of the melanoma coming back. We don't have enough evidence to know exactly how much skin to remove around the melanoma to give people the best chance at a good outcome.
We are doing this study to find out if an experimental drug called STK-012 (the study drug) is a safe and effective treatment for different types of cancer.
We are doing this study to help connect people with type 1 diabetes to research studies they may be eligible to join as participants.