Clinical Trials Directory

392 clinical trials found.
Brain and Spine Metastasis

We are doing this study to find out if an investigational drug called TYRA-300 (the study drug) is a safe and effective option for patients with locally advanced/metastatic urothelial cancer and other solid tumors.

Compensation: No
Oncology
Women's Health

We are doing this study to learn more about the causes of unsuccessful pregnancies. We want to compare samples of endometrial tissue from women who have experienced infertility with samples from women who have had children without fertility treatment. We hope this can help improve future options for women who are having difficulty with pregnancy.

Compensation: Yes
Ages: 18-42
Non-Oncology
Other
Bones, Joints and Muscles

We are doing this study to get a better understanding of why people are at higher risk of developing arthritis after ACL reconstruction surgery. We hope the information from this study can help improve recovery techniques and lower the risk of developing knee arthritis for people who have ACL surgery. We are partnering with UNC-Chapel Hill to do this study.

Compensation: Yes
Ages: 18-50
Non-Oncology
Duke University Hospital, Other

We are doing this study to evaluate the safety and effectiveness of a drug called isatuximab when it is used in
combination with lenalidomide and dexamethasone at lower doses. We want to know if this low dose combination can help patients with multiple myeloma achieve a better response while causing fewer or less severe side effects.

Compensation: No
Cancer Prevention and Screening

We are doing this study to better understand the unmet sexual health concerns of young adult male cancer survivors.

Compensation: Yes
Ages: 18-39
Oncology
Remote/online
Eyes and Vision

We are doing this study to learn more about variants in people's genes that cause cells in the back of the eye to function incorrectly and lead to a process called "retinal degeneration."

Compensation: Yes
Ages: 4-110
Non-Oncology
Duke University Hospital
Newborn and Neonatal Conditions/Birth Defects

We are doing this study to collect information about our state-of-the-art methods to care for the bladder and kidneys of babies born with spina bifida. We want to compare the results of these methods with other hospitals around the country that are following the same guidelines to protect the bladder and kidney health of infants with spina bifida. We and the other centers following these guidelines will regularly evaluate the outcomes of this care and modify the methods accordingly.

Compensation: No
Ages: 0
Non-Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to find out if the Vanquish Water Ablation System (VAPOR), which uses small amounts of steam to destroy cancer cells, is a safe and effective method for treating intermediate-risk prostate cancer.

Compensation: Yes
Ages: 50-110
Oncology
Duke University Hospital