Clinical Trials Directory

444 clinical trials found.
Hematologic Malignancies and Cellular Therapy

We are doing this study to determine whether specialty palliative care or primary palliative care is the best way to improve the quality of life and experience of patients and their caregivers.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to find out if an investigational drug called RGN-259 Thymosin Beta 4 eye drops solution (the study drug) is a safe and effective option for the treatment of neurotrophic keratopathy.

Compensation: No
Non-Oncology
Other

We are doing this study to test the feasibility and acceptability of an experimental communication device. This device was invented by a team from the Duke Pratt School of Engineering and is intended to help people with dementia and their caregivers. We want to know if this tool can be used to help people with dementia who live at home with their families.

Compensation: Yes
Ages: 60-110
Non-Oncology
Other
Sarcoma

We are doing this study to find out if a study drug called ivosidenib is a safe and effective option for locally advanced or metastatic conventional chondrosarcoma with an isocitrate dehydrogenase 1 (IDH1) mutation.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital

We are doing to study to help us design a questionnaire about sexual function specific to women who have mullerian anomalies. We hope this questionnaire can help us improve screening for and treatment of sexual concerns related to mullerian anomalies.

Compensation: Yes
Ages: 18-110
Duke University Hospital, Other
Skin Cancer - Non Melanoma Skin Disorders

We are doing this study to find out if an experimental drug called patidegib (the study drug) is a safe and effective option for people diagnosed with Gorlin syndrome. We want to know if it can help lower the number of basal cell carcinomas on the face.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Blood Disorders

We are doing this study to find out how see how easy or difficult it is to complete a hybrid (virtual and in-person) personalized exercise training program for older adults with sickle cell disease. The virtual training sessions will be done primarily on Zoom. This research is important to determine ways to improve movement capacity, heart health, strength, and quality of life in older adults living with sickle cell disease.

Compensation: Yes
Ages: 40-110
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to learn more about the connection between the brain and leg muscles in people who have chronic stroke. We want to understand how this connection affects the walking abilities of chronic stroke patients so we can provide better help to stroke patients who need to improve their motor function.

Compensation: Yes
Ages: 21-85
Non-Oncology
Duke University Hospital