Clinical Trials Directory
We are doing this study to find out if adding azithromycin to the routine single antibiotic preventative therapy can lower the risk of developing infections after a cesarean delivery.
We are doing this study to learn more about how 2 different classes of diabetes medications help lower the risk of heart disease. The types of diabetes medications that have been shown to reduce the risk of new or worsening heart disease are SGLT2 inhibitors and GLP-1 receptor agonists. We don't know which of these drugs might be preferable to reduce heart disease risk for diabetes patients, and we hope this study can help us find out which drug(s) may be the most appropriate for most patients.
We are doing this study to help develop a tool that doctors can use to figure out who might be at risk for developing muscle spasticity after a stroke. Spasticity is abnormal muscle stiffening that can lower people's strength and ability to move well. We hope this tool can help doctors catch this problem early and start treatment sooner to make therapy more effective.
We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.
People in this study will take part for about two years. During the study, they will have clinic visits, do some activities at home, and take part in phone or video check ins. They will have special heart scans and do blood tests at home to look for plaque, which is a buildup inside the heart blood vessels. If they qualify for the study, people will be placed into one of four groups by chance. They may take one study medicine, two study medicines together, or pills with no medicine. The medicines being studied are rosuvastatin and colchicine. Everyone will take one pill each day, use a Fitbit and a smartphone program, and have another heart scan at the end of the study to see if their heart health has improved.
We are doing this study to find the most effective, safe dose of an experimental drug called ONC-392 (the study drug). We want to know how well it works compared to the standard chemotherapy drug, docetaxel, for treating NSCLC.
We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.
In this study, people will first have a screening visit to make sure they can join and to check their pain and smoking habits. Next, they will have a training session to learn about the fake MRI scanner and how pain testing works. After that, they will have two brain scan sessions. For one scan, they will not smoke for 24 hours. For the other scan, they will smoke like normal. During each scan, they will feel heat pain and rate how it feels. Before and after each scan, they will answer questions about cravings, withdrawal, mood, and pain. There will be at least 2 days between the two scan sessions.