Clinical Trials Directory
In the TRANSFORM study, the study team will check your medical history and the medicines you take. They will measure your height, weight, blood pressure, and waist size. If your recent lab results are not in your medical record, you will give a fasting blood sample so doctors can check things like cholesterol, blood sugar, liver and kidney function, and signs of inflammation. You will be told the results of these regular lab tests. Another blood sample will be saved for future research to learn more about heart disease, including tests on your DNA, but you will not get the results from those future tests. The study team will tell you if your test results fall within the range needed to join the study. If they do, you will have a special heart scan called a coronary CT.
We are doing this study to find out how safe and effective it is to give people with recurrent glioblastoma two infusions of an experimental drug called lerapolturev (the study drug) in residual disease (within tumor margins) after surgery. After these two doses, we will give further doses of the study drug as injections in the subcutaneous area (under the skin) around the lymph nodes of the head and neck. We also want to know how well the study drug works compared to lomustine, which is a standard form of chemotherapy (drug used to kill cancer cells).
We are doing this study to find out if a personalized exercise program designed for lung cancer patients can help with recovery from lung surgery. The study's exercise program is delivered over the phone.
We created this registry for people with rare breast tumors to help us learn more about them and how to better treat people in the future.
We are doing this study to find out if an experimental drug called ravulizumab (the study drug) is a safe and effective option to prevent or reduce the severity of delayed graft function after people with end-stage kidney disease (ESKD) get a kidney transplant.
The purpose of this study is to see how a treatment called TMS can help people move their arms better. TMS stands for transcranial magnetic stimulation. It uses magnets to help the brain work in a different way. TMS is already approved to help people with depression, and doctors have also looked at how it helps people after a stroke. But scientists still need to learn the best way to use it to help people recover.
If you join this study, you will have the surgery your doctor planned. You can choose to use the regular tool or be randomly picked to use either the regular tool or a new one. Blood will be taken three times (before, during, and after surgery). Doctors will also check your regular cancer visits for one year. The study does not add extra visits or tests.
If you decide to join this study, doctors will first check your medical history and the medicines you are taking to see if you can be part of it. If you qualify, you will have several tests, including: - A heart scan (CT or MRI) - An ultrasound of your heart - A full check-up, including your heart and brain if you had a stroke before - Blood tests to check things like salt levels, kidney and liver health, and heart function - A heart test called an ECG - A walking test to see how far you can walk in 6 minutes - A survey called the Kansas City Cardiomyopathy Questionnaire to learn how you feel Some visits may take a long time, up to 8 hours.