Clinical Trials Directory

We are doing this study to find out if we can identify biomarkers that indicate the presence of ovarian cancer or indicate that it is likely to develop. Biomarkers are substances that can be released from cancer cells into the blood and can provide information on the following things: changes to someone's genes or DNA, how cancer cells will respond to cancer treatment, and whether cells are becoming resistant (no longer responding) to cancer treatment.

We are doing this study to help develop a tool that doctors can use to figure out who might be at risk for developing muscle spasticity after a stroke. Spasticity is abnormal muscle stiffening that can lower people's strength and ability to move well. We hope this tool can help doctors catch this problem early and start treatment sooner to make therapy more effective.

We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.

We are doing this study is to compare the two most common corrective surgeries in the U.S. for uterovaginal prolapse (UVP). For now, no high-quality data exists to help guide patients and surgeons on the best option for treatment of UVP. The goal of the study is to find out which surgery works best from a patient's perspective and has the lowest number of short-term and long-term medical problems.

We are doing this study to find the most effective, safe dose of an experimental drug called ONC-392 (the study drug). We want to know how well it works compared to the standard chemotherapy drug, docetaxel, for treating NSCLC.

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.

In this study, people will first have a screening visit to make sure they can join and to check their pain and smoking habits. Next, they will have a training session to learn about the fake MRI scanner and how pain testing works. After that, they will have two brain scan sessions. For one scan, they will not smoke for 24 hours. For the other scan, they will smoke like normal. During each scan, they will feel heat pain and rate how it feels. Before and after each scan, they will answer questions about cravings, withdrawal, mood, and pain. There will be at least 2 days between the two scan sessions.

We are doing this study to test a device that tracks urine and stool output from people when they are in the hospital. This study is important because if the device works, it can improve patients' comfort while they are recovering from a stem cell transplant.