Clinical Trials Directory

We are doing this study to understand how different factors, such as pain experiences and inflammation, may affect how acute back pain transitions to chronic back pain.

We are doing this study to find the most effective, safe dose of an experimental drug called iadademstat (the study drug). We want to know if the study drug is beneficial for people with R/R AML that have the FLT3 mutation when it is given in combination with gilteritinib.

You will get your own blood pressure monitor to use at home. We will teach you how to use it. You will check your blood pressure at home and share the numbers with your doctor's team for 12 months. The research team will also collect information in other ways, like: - Visits in person - Phone calls - Your medical records - Medicare data

We are doing this study to find out if an investigational implanted drug called Ocular Therapeutix Tyrosine Kinase Inhibitor Axitinib (the study drug) is a safe and effective option for people with nAMD.

If you agree to be in this study you will: - Have your aorta repaired with the Thoraflex Hybrid device - Have information collected from your medical record - Have study visits for up to 10 years after your aortic repair surgery (some may be completed via phone)

This study needs two overnight stays to give a special medicine called choline and to make sure it is safe. It also includes ten visits to the clinic over about sixteen months.

We are doing this to compare the results of early surgical intervention to medical therapy. We want to know if there is a difference in outcomes for these treatment options. We also want to track the health and progress of people with a large ascending aortic aneurysm (a bulge in the aorta caused by weakening in the artery wall).