Clinical Trials Directory

475 clinical trials found.
Cancer Immunotherapy

We are doing this study to find out if an experimental drug called STK-012 (the study drug) is a safe and effective treatment for different types of cancer.

Compensation: No
Oncology
Diabetes Mellitus

We are doing this study to help connect people with type 1 diabetes to research studies they may be eligible to join as participants.

Compensation: Yes
Ages: 16-50
Non-Oncology
Duke University Hospital, Other
Blood Disorders

We are doing this study to find out if an experimental drug called mezagitamab (the study drug) is a safe and effective option for people with chronic primary immune thrombocytopenia (ITP). We want to know if adding the study drug to someone's current treatment has any benefit.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if children and young adults with high-grade gliomas who have specific genetic changes (mutations) have better outcomes when they are treated with drugs that "target" those genetic changes. We first need to collect detailed information about the genetic changes within participants' brain tumors. If someone's brain tumor has a targeted genetic change, they may be eligible to participate in a clinical trial with a drug that specifically targets those genetic changes.

Compensation: No
Ages: 1-39
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called TL-895 (the study drug) is a safe and effective option for people with indolent systemic mastocytosis.

Compensation: No
Oncology
Gastrointestinal Cancer

What happens during the study? - You'll get the study medicine through an IV every 3 weeks - Doctors will take blood and urine samples - You'll have regular CT or MRI scans to check your health

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Surgery and Rehabilitation

The OTTAVA Robotic System is a special machine that helps doctors do surgery through very small openings in the skin. The doctor controls the robot, and the robot moves the tools inside the body based on the doctors hand movements. A tiny camera helps the doctor see inside the body during the procedure. If you join this study, your surgery will be done with the OTTAVA Robotic System, and you will have three study visits.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke Regional Hospital
Brain, Spinal Cord and Nerves

This study lasts for 90 days. People who join will wear a cloth cap with special sensors on their head. A computer will help decide which group they are in. Some people will get a real treatment, and others will be in a control group, which means they do not get the real treatment. After each of the one, two, or three treatment sessions, people will answer ten questions about how they feel. A doctor or helper will also check how their brain and body are working for five minutes. One day after the treatment, they will get a brain scan and a test to see how blood moves in their brain. They will also have short check-ups in person on day one and day four, a phone call on day thirty, and another in-person visit on day ninety.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital