Clinical Trials Directory

438 clinical trials found.
Blood Disorders

We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.

Compensation: No
Non-Oncology
Kidneys, Bladder and Urinary System

We are doing this study is to compare the two most common corrective surgeries in the U.S. for uterovaginal prolapse (UVP). For now, no high-quality data exists to help guide patients and surgeons on the best option for treatment of UVP. The goal of the study is to find out which surgery works best from a patient's perspective and has the lowest number of short-term and long-term medical problems.

Compensation: Yes
Ages: 18-80
Non-Oncology
Other
Thoracic Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called ONC-392 (the study drug). We want to know how well it works compared to the standard chemotherapy drug, docetaxel, for treating NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Heart and Circulation

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.

Compensation: Yes
Ages: 75-110
Non-Oncology
Pickett Road Research, Kannapolis, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to test a device that tracks urine and stool output from people when they are in the hospital. This study is important because if the device works, it can improve patients' comfort while they are recovering from a stem cell transplant.

Compensation: No
Oncology
Lungs and Breathing

We are doing this to develop a test that could help predict a common complication after lung transplant called primary graft dysfunction (PGD). Examining the medical records of transplant recipients and their donors will help us find the data we need to create this prediction tool.

Compensation: No
Non-Oncology
Radiation Oncology

We are doing this study to measure quality of life and compare signs such as tiredness, feeling of unease, discomfort in the stomach, and pain in patients who have been treated with either PLA or HIGRT for liver cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Other