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438 clinical trials found.
Kidneys, Bladder and Urinary System

We are doing this study to find out if a medical technology called the Revi System active therapy (system is being implanted and activated) is better than non-active Revi system therapy (system is being implanted but not activated) for the treatment of urinary urge incontinence (UUI).

Compensation: Yes
Ages: 18-110
Non-Oncology
Other
Eyes and Vision

We are doing this study to find out is an experimental drug called RGX-314 can help improve or preserve vision. We will compare how this drug works to Eylea®, which is an approved therapy for age-related macular degeneration.

Compensation: Yes
Ages: 50-89
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to see if an experimental drug called RMC-6236 (the study drug) is a safe and effective option for treating colorectal or pancreatic cancer when it is combined with different chemotherapy drugs.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to compare 2 different procedures for treating cervical cancer and find out which approach has the best outcomes for patients. The two procedures that we will compare are open surgery with a single large incision (laparotomy) and robotic assisted laparoscopy (small incision surgery). We do not know which option is preferable in most cases, and we hope this study can help us find out which procedure is the better choice for patients.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Lungs and Breathing

We are doing this study to find out if an investigational drug called belumosudil (the study drug) is an option for the treatment of chronic lung allograft dysfunction (CLAD). The study drug is taken by mouth.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Research for Healthy Adults

We are doing this study to understand how sex hormones (chemicals that tell cells and body parts to do certain things), such as estrogens and androgens, impact skin diseases like hidradenitis suppurativa (HS). To better understand this, we are enrolling both people who have diagnosed skin diseases and healthy volunteers who have no skin issues.

Compensation: Yes
Ages: 18-46
Non-Oncology
Duke University Hospital