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474 clinical trials found.
Pregnancy Concerns

We are doing this study to find out if adding azithromycin to the routine single antibiotic preventative therapy can lower the risk of developing infections after a cesarean delivery.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about how 2 different classes of diabetes medications help lower the risk of heart disease. The types of diabetes medications that have been shown to reduce the risk of new or worsening heart disease are SGLT2 inhibitors and GLP-1 receptor agonists. We don't know which of these drugs might be preferable to reduce heart disease risk for diabetes patients, and we hope this study can help us find out which drug(s) may be the most appropriate for most patients.

Compensation: Yes
Ages: 40-80
Non-Oncology
Remote/online
Brain, Spinal Cord and Nerves

We are doing this study to help develop a tool that doctors can use to figure out who might be at risk for developing muscle spasticity after a stroke. Spasticity is abnormal muscle stiffening that can lower people's strength and ability to move well. We hope this tool can help doctors catch this problem early and start treatment sooner to make therapy more effective.

Compensation: Yes
Ages: 21-110
Non-Oncology
Duke University Hospital
Blood Disorders

We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.

Compensation: No
Non-Oncology
Thoracic Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called ONC-392 (the study drug). We want to know how well it works compared to the standard chemotherapy drug, docetaxel, for treating NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Older Adults/Aging

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.

Compensation: Yes
Ages: 75-110
Non-Oncology
Pickett Road Research, Kannapolis, Other

In this study, people will first have a screening visit to make sure they can join and to check their pain and smoking habits. Next, they will have a training session to learn about the fake MRI scanner and how pain testing works. After that, they will have two brain scan sessions. For one scan, they will not smoke for 24 hours. For the other scan, they will smoke like normal. During each scan, they will feel heat pain and rate how it feels. Before and after each scan, they will answer questions about cravings, withdrawal, mood, and pain. There will be at least 2 days between the two scan sessions.

Compensation: Yes
Ages: 21-65
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to test a device that tracks urine and stool output from people when they are in the hospital. This study is important because if the device works, it can improve patients' comfort while they are recovering from a stem cell transplant.

Compensation: No
Oncology