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569 clinical trials found.
Blood Disorders

In this study, everyone will receive a medicine called ianalumab that is given through a vein. People will get this treatment once every four weeks for four doses. During this time, they will come to the clinic each week to have blood tests to check their platelet levels. They will also take another medicine chosen by the study doctor to help increase platelets. After the last dose of the study medicine, participants will continue to have weekly blood checks for 16 weeks. After that, they will have blood checks once a month for one year. The goal is to closely watch how their blood counts change over time and see how well the treatment works.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study to compare two commonly used treatment choices for early-stage breast cancer in premenopausal women. We want to know if either option is a better choice than the other.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Radiation Oncology

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if a blood test for circulating tumor DNA (ctDNA) can provide information that might help doctors figure out the most appropriate therapy for patients with colon cancer after they have surgery.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Radiation Oncology

Compensation: No
Oncology
Radiation Oncology

We are doing this study to find out if adding radiation therapy has any positive benefit when it is added to the usual treatment regimen for this form of cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Radiation Oncology

Group 1: People in this group will get the usual chemotherapy and radiation treatment for this cancer. They will have radiation 5 days a week for 4 to 5 weeks. That means about 20 treatments in total. Group 2: People in this group will get the usual chemotherapy and a new way of giving radiation. This way uses fewer treatments with a higher dose. They will have radiation up to 2 days a week for up to 4 weeks. That means about 5 treatments in total.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Radiation Oncology

We are doing this study to see if radiation and chemotherapy can be done instead of an extensive surgical removal of the groin lymph nodes for patients with vulvar cancer whose disease has spread to the sentinel node. We are doing this study because we want to find out if this approach is better or worse than the usual approach for vulvar cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital