Clinical Trials Directory

442 clinical trials found.
Eyes and Vision

We are doing this study to find out if an experimental drug called brepocitinib (the study drug) is a safe and effective option people with non-infectious uveitis (NIU).

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Research for Children and Teenagers

If you choose to join this study, we will ask you questions about:

  • Your life at home
  • Your life at school
  • Your medical needs
We will ask you to answer these questions each year during one of your regular clinic visits.

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called quizartinib (the study drug) for people with acute myeloid leukemia (AML) who do not have a FLT3-ITD mutation and who have not completed any treatment for their disease.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out how safe and effective it is to give people with recurrent glioblastoma two infusions of an experimental drug called lerapolturev (the study drug) in residual disease (within tumor margins) after surgery. After these two doses, we will give further doses of the study drug as injections in the subcutaneous area (under the skin) around the lymph nodes of the head and neck. We also want to know how well the study drug works compared to lomustine, which is a standard form of chemotherapy (drug used to kill cancer cells).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to find out if a personalized exercise program designed for lung cancer patients can help with recovery from lung surgery. The study's exercise program is delivered over the phone.

Compensation: Yes
Ages: 65-110
Oncology
Duke University Hospital
Breast Cancer

We created this registry for people with rare breast tumors to help us learn more about them and how to better treat people in the future.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called RMC-6236 (the study drug) is a safe and effective option for people with metastatic pancreatic ductal adenocarcinoma (PDAC). We want to see how well the study drug works compared to the standard chemotherapy regimen for PDAC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Digestive System

We are doing this study to learn more about the long-term effectiveness of an approved medicine that is prescribed for the treatment of EoE. We want to know how will dupilumab (Dupixent®) works over time when EoE patients and their doctors choose it as therapy. Dupilumab was approved by the FDA in May 2022 to treat EoE and was the first drug approved for this purpose.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital