Clinical Trials Directory

We are doing this study to find out if an investigational drug called OpRegen (the study drug) is a safe and effective option for older adults who have geographic atrophy (GA) secondary to age-related macular degeneration (AMD). We also want to know if a procedure called subretinal surgical delivery is an effective way to give people the study drug.

If you are able to join this study, you will be placed by chance into one of three groups. One group will get 225 milligrams of the study drug GSK6519754, another will get 300 milligrams, and the third group will get a placebo, which has no medicine. You will get your assigned injection once every four weeks for four years. During the study, which lasts a little over four years, you will have at least fifty four visits. At these visits, you will have blood tests, body and liver scans, ultrasounds, a liver biopsy, and questionnaires to check your health and how the treatment is working.

If you can join this study, you will be placed by chance into one of three groups. One group will get 225 milligrams of the study medicine called GSK6519754, another group will get 300 milligrams, and the third group will get a placebo, which has no medicine. Most people will receive the study medicine. You will get the injection once every four weeks for several years. During the study, you will come to the clinic many times. At these visits, doctors will do blood tests, body and liver scans, ultrasounds, and ask you to fill out questionnaires to check your health and how the treatment is working.

This study tests a new cancer medicine. It has 3 parts: - Screening (up to 28 days): You'll get tests like heart checks, scans, and blood work. - Treatment: You'll visit the clinic every 3 weeks to get the study drug. There are different groups testing the drug with other treatments for cancers like ovarian and endometrial. - Follow-Up: After treatment, you'll have check-ups at 30, 60, and 90 days, plus long-term follow-up with more tests.

Completing an 8 question survey

We are doing this study to understand how hand transplantation can help you with your daily activities compared to before the transplant.

We are doing this study to better understand how HIV affects the body.