Clinical Trials Directory

276 clinical trials found.
Skin Cancer - Melanoma

We are doing this study to find out if an experimental study drug called RP1 is a safe and effective treatment for your cancer. We want to know how the drug works on its own and when it is combined with a cancer drug called nivolumab.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out is an experimental drug called RGX-314 can help improve or preserve vision. We will compare how this drug works to Eylea®, which is an approved therapy for age-related macular degeneration.

Compensation: Yes
Ages: 50-89
Non-Oncology
Duke University Hospital
Skin, Hair and Nails

We are doing this study to find out if an experimental drug called rocatinlimab (the study drug) is a safe and effective option for adolescents with atopic dermatitis (eczema).

Compensation: Yes
Ages: 12-18
Non-Oncology
Other
Skin, Hair and Nails

We are doing this study to understand how sex hormones (chemicals that tell cells and body parts to do certain things), such as estrogens and androgens, impact skin diseases.

Compensation: No
Non-Oncology
Heart and Circulation

We are doing this study to determine the effect of single vs multiple arterial revascularization (this is the restoration of blood flow to an organ) for female patients undergoing coronary artery bypass surgery (CABG).

Compensation: No
Non-Oncology
Research for Children and Teenagers

We are doing this study to learn more about mutations in the DNA of a gene called PCDH15. This mutation causes cells in the back of the eye to stop working (called "retinitis pigmentosa").

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare the early treatment (before you have cancer symptoms) of Venetoclax and Obitnutuzumab (V-O) to the usual treatment of V-O after you have cancer symptoms. This study will help doctors figure out if early treatment is better, the same, or worse than the usual approach of waiting until the patient has cancer symptoms before starting treatment.

Compensation: No
Oncology
Thoracic Cancer

We are doing this study to find out if a pair of investigational drugs called ramucirumab and pembrolizumab (the study drugs) are a safe and effective treatment for your form of cancer. We want to know how well the study drugs work in comparison to the standard treatment for Stage IV or recurrent NSCLC.

Compensation: No
Oncology