Clinical Trials Directory

If you are able to join this study, you will be placed by chance into one of three groups. One group will get 225 milligrams of the study drug GSK6519754, another will get 300 milligrams, and the third group will get a placebo, which has no medicine. You will get your assigned injection once every four weeks for four years. During the study, which lasts a little over four years, you will have at least fifty four visits. At these visits, you will have blood tests, body and liver scans, ultrasounds, a liver biopsy, and questionnaires to check your health and how the treatment is working.

If you can join this study, you will be placed by chance into one of three groups. One group will get 225 milligrams of the study medicine called GSK6519754, another group will get 300 milligrams, and the third group will get a placebo, which has no medicine. Most people will receive the study medicine. You will get the injection once every four weeks for several years. During the study, you will come to the clinic many times. At these visits, doctors will do blood tests, body and liver scans, ultrasounds, and ask you to fill out questionnaires to check your health and how the treatment is working.

Completing an 8 question survey

If a child joins this study, they will be placed into one of two groups by chance. One group will receive a medicine called Cipepofol, and the other group will receive a medicine called Propofol. These medicines are given through a vein to help the child fall asleep before surgery. Most children will receive Cipepofol, while a smaller number will receive Propofol. All children will still receive normal anesthesia care during surgery. Before surgery, there will be a screening visit with tests such as a physical exam, blood tests, urine tests, heart checks, and vital signs. On the day of surgery, more checks will be done. After surgery, the study team will call three times to see how the child is doing. Participation lasts for up to 29 days after surgery.

We are doing this study to understand how hand transplantation can help you with your daily activities compared to before the transplant.

We are doing this study to better understand how HIV affects the body.