Clinical Trials Directory

435 clinical trials found.
Kidneys, Bladder and Urinary System

We are doing this study to assess the long-term safety of an experimental drug called tegoprubart (the study drug) when it is given in combination with a standard immunosuppressive medicine, mycophenolate or mycophenolic acid, after a kidney transplant. The study will also look at the function and health of the implanted kidney and will assess how well the study drug can lower the risk of diabetes and transplant rejection.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called LY3962673 (the study drug) is a safe and effective option for cancer that has a KRAS G12D mutation. We are also trying to find the best dose level to use.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called AbbV-383 (the study drug) is safe and effective for patients with relapsed/refractory multiple myeloma.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Skin, Hair and Nails

We are doing this study to find out if an experimental drug called upadacitinib (the study drug) is a safe and effective option for people with moderate to severe hidradenitis suppurativa (HS) who did not get adequate relief from standard treatment.

Compensation: Yes
Ages: 12-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about the sounds coming from a Doppler device when testing arteries. The recording will be used to train a computer program to compare the sounds from healthy arteries to non-healthy arteries.

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called MGD024 (the study drug) is a safe and effective option for patients with different cancers of the blood or bone marrow that have relapsed or do not respond to standard therapy. We will test how the study drug works at different doses during this study in order to find the most effective dose.

Compensation: No
Oncology
Biobank / Biospecimen Collections

A registry is a database of information (data) about patients living with a specific condition. Scientists study the information in the registry to increase what we know about the condition so we can develop better treatments in the future. We have created this registry to collect and store medical data, blood and urine samples from people with an autoimmune disease or rheumatic conditions during pregnancy for possible use in future research.

Compensation: No
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about ATTR and its different variants and how they can can be better diagnosed, managed, and treated.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital