Clinical Trials Directory

473 clinical trials found.
Gynecologic Cancer

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Heart and Circulation

We are using this registry to gather data about the use and safety of certain medical devices used in a part of the body called the aorta and/or iliac arteries, which are large blood vessels that run inside the chest, abdomen, and groin area. The name of the devices being looked at are the GORE® EXCLUDER® Conformable AAA Endoprosthesis (EXCC Device) or the GORE® EXCLUDER® Iliac Branch Endoprosthesis (IBE Device).

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Heart and Circulation

We are doing this study to collect data about the use and safety of the GORE TAG Conformable Thoracic Stent Graft®. This device is approved by the FDA for the endovascular repair of medical conditions of the aorta (the large blood vessel that runs inside the chest and abdomen).

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are dong this study to collect information about the use of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device). The TAMBE Device was approved by the FDA in 2024 for use in endovascular repair as a treatment for patients with thoracoabdominal and pararenal aortic aneurysms. We want to get data about how well the device performs in the patients who choose to get this implant.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out if an investigational drug called RO7446603 (the study drug) is a safe treatment for diabetic macular edema. We will give the drug at different doses and also want to understand the way the body processes the drug.

Compensation: Yes
Ages: 18-90
Non-Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out if an investigational drug called OpRegen (the study drug) is a safe and effective option for older adults who have geographic atrophy (GA) secondary to age-related macular degeneration (AMD). We also want to know if a procedure called subretinal surgical delivery is an effective way to give people the study drug.

Compensation: Yes
Ages: 50-110
Non-Oncology
Duke University Hospital
Gynecologic Cancer

This study tests a new cancer medicine. It has 3 parts: - Screening (up to 28 days): You'll get tests like heart checks, scans, and blood work. - Treatment: You'll visit the clinic every 3 weeks to get the study drug. There are different groups testing the drug with other treatments for cancers like ovarian and endometrial. - Follow-Up: After treatment, you'll have check-ups at 30, 60, and 90 days, plus long-term follow-up with more tests.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital