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403 clinical trials found.
Mental Health, Behavior, and Substance Abuse

We are doing this study to compare 2 different approaches to help people quit smoking. We want to know which of these approaches is most likely to help smokers who have a mental illness and want to stop smoking.

Compensation: Yes
Ages: 18-110
Non-Oncology
Remote/online
Mental Health, Behavior, and Substance Abuse

We are doing this study to learn more about how well a study intervention works to reduce distress caused by misophonia. This intervention combines neurostimulation and skills-based training that is designed to help people think differently.

Compensation: Yes
Ages: 18-55
Non-Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if an experimental drug called MK-2870 (the study drug) is an option for patients with endometrial cancer. We want to know how well it works compared to standard chemotherapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called bomedemstat or hydroxyurea in people with essential thrombocythemia (ET). We also want to know which of these options works best for most people.

Compensation: No
Oncology
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.

Compensation: No
Oncology
Biobank / Biospecimen Collections

The purpose of this study is to better understand how prenatal maternal health, such as higher body mass, and well-being, such as mental health, are related to early child development. We are especially interested in identifying the factors that influence young children's ability to regulate their emotions. We hope that any new information we learn from this study could benefit young children in the years to come. El propósito de este estudio es comprender mejor cómo la salud prenatal de la madre, como una mayor masa corporal, y el bienestar, como la salud mental, están relacionados con el desarrollo tempano de los niños. Estamos especialmente interesados en identificar los factores que influyen en la capacidad de los niños pequeños para regular sus emociones. Esperamos que cualquier información nueva que obtengamos de este estudio pueda beneficiar a los niños pequeños en los años venideros.

Compensation: Yes
Ages: 18-40
Non-Oncology
Duke University Hospital, Other
Gastrointestinal Cancer

We are doing this study to see how tucatinib, trastuzumab, and mFOLFOX6 work to treat cancer of your colon or rectum that is HER2-positive with mFOLFOX6 alone or combined with bevacizumab.

Compensation: No
Oncology
Radiation Oncology

We are doing this study to find out if the study intervention (additional delayed MRI sequences) can tell the difference between radiation damage and tumor recurrence.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital