Clinical Trials Directory

276 clinical trials found.
Lungs and Breathing

We are doing this to develop a test that could help predict a common complication after lung transplant called primary graft dysfunction (PGD). Examining the medical records of transplant recipients and their donors will help us find the data we need to create this prediction tool.

Compensation: No
Non-Oncology
Brain and Spine Metastasis

We are doing this study to find out if an investigational drug called PRL-02 (the study drug) is a safe and effective method to lower levels of male hormones during treatment for prostate cancer. The study drug is an injectable form of a drug called abiraterone.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called Rusfertide (the study drug) is a safe and effective treatment for polycythemia vera (PV). Rusfertide (also known as PTG-300) lowers the level of iron in the blood which is required for production of red blood cells.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called birtamimab (the study drug) is a safe and effective treatment for amyloidosis. We want to find the most appropriate dose and schedule to give patients the study drug.

Compensation: No
Oncology
Radiation Oncology

We are doing this study to measure quality of life and compare signs such as tiredness, feeling of unease and discomfort in the stomach and pain in patients who have been treated with either PLA or HIGRT for liver cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Other
Bones, Joints and Muscles

We are doing this study to understand what causes people to have persistent pain in their muscles, bones, ligaments, tendons, or nerves.

We will also work with people to think about if their current way for managing pain are working and help them find better strategies for coping with pain in order to reducing pain, disability and distress.

Compensation: No
Non-Oncology
Gastrointestinal Cancer

We are doing this study to learn if a new study drug called PT-112 is a safe and effective treatment for metastatic, castrate-resistant prostate cancer. This study is one of the first times PT-112 is being tested in humans. The study drug has been shown to induce cell death in tumor cells, and shrink tumors in animal studies. This study will also teach us how long the study drug stays in your body after you receive it.

Compensation: No
Oncology
Research for Healthy Adults

We created this registry to have a database of healthy people who are interested in participating in research about lung health and breathing. We will use this registry to reach out to people and notify them about research studies in which they might be interested.

Compensation: No
Non-Oncology