Clinical Trials Directory

276 clinical trials found.
Lungs and Breathing

We maintain this registry to have a database of people with any type of lung or breathing disorder who are interested in participating in research about their lung condition.

Compensation: No
Ages: 18-65
Non-Oncology
Duke University Hospital
Research for Children and Teenagers

If you choose to join this study, we will ask you questions about:
-Your life at home
-Your life at school
-Your medical needs.

We will ask you to answer these questions each year during one of your regular clinic visits.

Compensation: No
Non-Oncology
Bones, Joints and Muscles

We are doing this study to get a better understanding of how exercise affects the motion and mechanics of the shoulder joint in people who have shoulder instability and are planning to have shoulder surgery. We hope the information we gain from this study can improve treatment methods for injuries like shoulder dislocations or rotator cuff tears.

Compensation: Yes
Ages: 15-35
Non-Oncology
Duke University Hospital, Other
Breast Cancer

We created this registry for people with rare breast tumors to help us learn more about them and how to better treat people in the future.

Compensation: No
Oncology
Skin Cancer - Non Melanoma Skin Disorders

We are doing the study to understand how your body reacts to the study drug, Cemiplimab.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Heart and Circulation

If your child is eligible and you allow them to join the study, they will:
- Get a random assignment (like a coin flip) to 1 of 2 groups
-- One group will be treated with numbing medicine at the incision site to lower their pain after surgery
-- The other group will have the nerves around the incision site blocked using ultrasound guidance to lower their pain after surgery

Both of these procedures are routinely performed by clinicians to help manage pain after surgery. We do not know which procedure is better for most children, and we hope this study will help us find out.

We will also ask you and your child to fill out a few surveys during your time in the hospital. We will call you about 30 days after your child's procedure to see how they are doing and end their study participation.

Compensation: Yes
Ages: 0-17
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to find out if an experimental device is a safe and effective method to repair a leaking mitral valve. The device is called MitraClip, and it is placed in the heart in a less invasive manner that uses a catheter. We want to know how well this device works compared to standard mitral valve repair surgery, which is a more invasive procedure.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Phase I

We are doing this study to find out the safest and most effective dose of the study drug (RP-3500) is when given alone or in combination with talazoparib.

Compensation: No
Oncology