Clinical Trials Directory

We are doing this study to find out if an investigational vaccine (HydroVax-005 CHIKV - the study vaccine) is a safe and effective option to protect against chikungunya virus. Chikungunya virus is spread by mosquitos that are most common in Africa, Asia, and India. Infection with the virus can cause serious disease in older adults, children, and people with weaker immune systems.

We are doing this study to test an experimental simulation of "extravehicular activities" (EVAs), which are more commonly known as spacewalks. We want to know if this simulation will provide good training for astronauts who will have to perform EVAs during their space missions.

We are doing this study to learn more about changes in nasal tissue in people that have COVID-19. Many COVID-19 patients have reported a change in sense of smell and we would like to find out why that is.

We are using you or your child's medical information in this study to better understand the diagnosis, treatment, and complications of Spina Bifida.

We created the Registry for Brain Health to help you improve your brain health and get involved in research studies. The number of people in North Carolina affected by memory disorders, such as Alzheimer's disease and other forms of dementia, is going up. To change that, we must work together, stay informed, and get involved. We are enrolling both people who have memory problems and people who are healthy and do not have memory problems.

We are doing this study to learn more about the rare diagnosis of New Daily Persistent Headache (NDPH). We want to get more information about why some children and young people develop this condition and how it is different from traditional headaches, like migraines. This knowledge can help us to begin developing possible treatments for NDPH.

We are doing this study to find out if an investigational called Daromun (the study drug) is a safe and effective treatment for melanoma. We want to know if treating people with the drug before surgery to remove tumors can lower the chance of cancer recurrence.

We are doing this study to learn more about the following symptoms that can be related to primary hyperparathyroidism: confusion, difficulty remembering and focusing, memory fog, changes in a person's normal behavior, feeling "blue", increased anxiety, increased agitation, and trouble performing daily activities, like driving and remembering appointments. We want to know how much these symptoms change in older adults after they have endocrine surgery.