Clinical Trials Directory

403 clinical trials found.
Gynecologic Cancer

We are doing this study to find out if neratinib combined with palbociclib is better than neratinib alone when it comes to treating HER2-positive tumors.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Brain, Spinal Cord and Nerves

We are doing this study to learn more about how right hemisphere brain damage (RHD) from a stroke can affect people's ability to communicate. We want to improve treatments to help stroke survivors regain their ability to communicate.

Compensation: Yes
Ages: 18-110
Non-Oncology
Other
Breast Cancer

We are doing this study to find out if adding a drug called tucatinib to the usual treatment of T-DM1 on its own can help prevent breast cancer from returning.

Compensation: No
Oncology
Heart and Circulation

We are doing this study to learn if SAPIEN 3 valve system is safe and will work with adults and children who have a dysfunctional right ventricular outflow tract (RVOT) conduit or have an implanted valve in the pulmonic position.

Compensation: Yes
Ages: 0-100
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare the study drug, lutetium-177 edotreotide, to existing standard-of-care therapies.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We want to find out if a study drug called larotrectinib is an effective treatment for brain tumors in children and young adults. We want to learn how well it works to shrink brain tumors when used alone or when given with standard chemotherapy or after radiation therapy.

Compensation: No
Ages: 0-21
Oncology
Duke University Hospital

We are doing this study to learn how to best support young women making decisions about breast cancer surgery. We want to know what makes women feel uncertain about their decision-making so we can become better at providing the information they need. This study involves testing a web-based decision support tool that is designed to help young women with newly diagnosed breast cancer with their surgical decisions.

Compensation: Yes
Ages: 18-44
Remote/online
Breast Cancer

We are doing this study to find out if the use of continuous glucose monitors (CGMs) is worthwhile to help breast cancer patients and their providers monitor for hyperglycemia, or high blood sugar, during chemotherapy. A CGM is a small, wearable sensor that is attached to the skin to frequently measure your blood sugar level, and can share the measurements to your smartphone and to your medical team.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital