Clinical Trials Directory

402 clinical trials found.
Brain and Spine Metastasis

We are doing this study to see if the combination of an experimental drug called BGB-3245 (the study drug) and panitumumab is a safe and effective option for patients who have colorectal or pancreatic cancer with an RAS mutation.

Compensation: No
Oncology
Thoracic Cancer

We are doing this study to find out if an investigational drug called bemcentinib (the study drug) is a safe and effective option when it is combined with the standard therapy for non-small cell lung cancer (1 immunotherapy drug and 2 chemotherapy drugs).

Compensation: No
Oncology
Gynecologic Cancer

We are doing this study to collect data, liquid biopsies (blood and urine), and cancer specimens from women with primary epithelial ovarian, peritoneal, or tubal cancer. We are using this information and these samples to create a biobank that might identify future therapeutic targets and help develop new therapies for these types of cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Trauma and Emergency Department Studies

We are doing this study to get a better understanding of how several different factors influence our overall health. The factors we will study include:

  • Trauma
  • Social determinants of health (nonmedical factors that can influence health)
  • Allostatic load (wear and tear on the body)
  • Biological response to trauma

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called BNT142 (the study drug) is a safe and effective treatment for select cancers with solid tumors that test positive for a protein called Claudin 6 (CLDN6).

Compensation: No
Oncology
Skin, Hair and Nails

Collection of samples will allow for increased and more focused research on skin conditions and perhaps eventually lead to the development of improved treatment outcomes.

Compensation: No
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find the most safe and effective dose of an experimental drug called BMS-986460 (the study drug) for men with metastatic castration resistant prostate cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We created this healthy volunteer registry for people who would like to participate in brain imaging research studies. These studies use structural and functional MRI data to study areas of the brain associated with movement, memory, attention, and perception.

Compensation: Yes
Ages: 18-80
Non-Oncology
Duke University Hospital