Clinical Trials Directory

We are doing this study to find out if an experimental drug called avexitide (the study drug) is a safe and effective option to prevent or reduce the severity of hypoglycemia episodes for people who have post-bariatric hypoglycemia following Roux-en-Y gastric bypass.

We are doing this study to find out if a program called AYA STEPS has a positive benefit for young people who are treated for cancer. We want to know how well this program can help cancer survivors younger than 40 manage any physical or emotional symptoms they have after treatment, and we also want to see if the program can help them be more engaged with follow-up care.

If you qualify for the study, a computer will choose your medicine by chance. This means you could get AZD0780 or a pill that does not have medicine, called a placebo. It is like flipping a coin, so you have a 1 in 2 chance of getting AZD0780. Neither you nor your doctor will know which one you get. You will take one pill by mouth every day. Each pill is 30 milligrams. You will visit the study site up to 15 times. These visits will happen at the start and then at different weeks, like week 0, 2, 4, 12, and so on. Each visit will take about 1 to 2 hours. Your doctor will tell you what tests and steps you need to do. Before each visit, you cannot eat or drink anything except water for at least 8 hours. You can drink water during this time.

We are doing this study promote the importance of quitting smoking for pregnant women and to improve how providers can help their patients quit smoking.

We are doing this study to find out if pictures taken of the back of the eye (retina) using a special type of camera called Optical Coherence Tomography (OCT) can predict how well a baby will be able to see and how their brain works at school age. El propósito de este estudio es determinar si las fotos tomadas del fondo de ojo (retina) usando una cámara especial que se llama Tomografía de coherencia Óptica (OCT), puede predecir la visión y como el cerebro funciona a la edad escolar.

We are doing this study to test different drugs to see if they are safe and helpful for adults who are admitted in the hospital with acute respiratory distress syndrome (ARDS) compared to placebo (a substance that looks like a drug but does not contain an active drug).

We are doing this study to compare the outcomes of 2 treatments for women with stress urinary incontinence (SUI): transurethral bulking agent (TBA) and single-incision sling (SIS). Both treatments are FDA-approved and can help improve SUI symptoms, but they have not been directly compared to each other to see which treatment is better for certain patients and under what circumstances. We hope this study can help women and their doctors find out which option is most likely to have the best results. Current evidence suggests that TBA and SIS are less effective than a traditional full-length mid-urethral sling procedure, but both options are less invasive and less likely to cause complications afterward.

We are doing this study to find out whether certain immunotherapy drug combinations with and without chemotherapy given before and after surgery for mesothelioma can help prevent the tumor from coming back. The two immunotherapy drugs, durvalumab and tremelimumab, are called immune checkpoint inhibitors and are used to activate the immune system against cancer. Immune checkpoint inhibitors are now approved for mesothelioma for patients who cannot undergo surgery, but they are not approved prior to surgery. The chemotherapy drugs (cisplatin or carboplatin and pemetrexed) are standard options for the treatment of mesothelioma.