Clinical Trials Directory

438 clinical trials found.
Lungs and Breathing

We are doing this study to find out how certain breathing exercises can affect people's ability to swim and exercise in underwater conditions. We want to find out what effects this training has and how it is influenced by other factors, like water temperature, medication use, or sleep.

Compensation: Yes
Ages: 18-45
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called mosunetuzumab (the study drug) is a safe and effective option for patients with follicular lymphoma.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Older Adults/Aging

We are doing this study to compare 3 different kinds of brain training to find out which is most effective in improving cognitive outcomes and everyday functioning for people with mild cognitive impairment or memory loss. Participants who take part in this study will do the brain training at home.

Compensation: Yes
Ages: 55-89
Non-Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if neratinib combined with palbociclib is better than neratinib alone when it comes to treating HER2-positive tumors.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Brain, Spinal Cord and Nerves

We are doing this study to learn more about how right hemisphere brain damage (RHD) from a stroke can affect people's ability to communicate. We want to improve treatments to help stroke survivors regain their ability to communicate.

Compensation: Yes
Ages: 18-110
Non-Oncology
Other
Biobank / Biospecimen Collections

We are doing this study to identify new signs and symptoms of inflammatory bowel disease (IBD) in children and young adults. We want to improve at predicting the future course of IBD so that we can treat it better and faster. We also hope this study will help us learn how IBD develops so that we can make new treatments for IBD.

Compensation: Yes
Ages: 2-21
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn if SAPIEN 3 valve system is safe and will work with adults and children who have a dysfunctional right ventricular outflow tract (RVOT) conduit or have an implanted valve in the pulmonic position.

Compensation: Yes
Ages: 0-100
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study to learn how to best support young women making decisions about breast cancer surgery. We want to know what makes women feel uncertain about their decision-making so we can become better at providing the information they need. This study involves testing a web-based decision support tool that is designed to help young women with newly diagnosed breast cancer with their surgical decisions.

Compensation: Yes
Ages: 18-44
Oncology
Remote/online