Clinical Trials Directory

324 clinical trials found.
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called iberdomide (the study drug) is a safe and effective option for multiple myeloma (MM). We also want to what the most appropriate dose and timing for taking the study drug should be.

Compensation: No
Oncology
Brain, Spinal Cord and Nerves

We are doing this study to find out if an experimental cell therapy called NRTX-1001 (the study drug) is a safe and effective treatment for drug-resistant mesial temporal lobe epilepsy (MTLE). We want to know if the study drug can reduce seizures in people who are not getting relief from conventional treatments.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to find out if an investigational drug called CG0070 (the study drug) is safe and effective for patients who have NMIBC that does not respond to BCG treatment.

Compensation: Yes
Ages: 18-90
Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to learn if a combination of chemotherapies and immunotherapies (carboplatin, cabazitaxel, nivolumab and ipilimumab) slows cancer growth in patients with metastatic neuroendocrine or aggressive variant prostate cancer.

We also want to learn about the types of side effects that patients have while they are taking these study drugs together.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Heart and Circulation

We are doing this study to learn more about children with tricuspid atresia. We hope to improve care for patients with this condition in the future.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital
Women's Health

We created this registry to have database of people who are interested in participating in research about chronic pain.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Ear, Nose and Throat

We are doing this study to use CT pictures, called cone-beam images, to look at the severity of cleft-induced nasal dysfunction in order to improve breathing after surgery.

Compensation: No
Non-Oncology
Research for Children and Teenagers

We are doing this study to improve care for people with cleft lip and/or cleft palate.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital