Clinical Trials Directory

442 clinical trials found.
Gynecologic Cancer

We are doing this study to collect data, liquid biopsies (blood and urine), and cancer specimens from women with primary epithelial ovarian, peritoneal, or tubal cancer. We are using this information and these samples to create a biobank that might identify future therapeutic targets and help develop new therapies for these types of cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called BNT142 (the study drug) is a safe and effective treatment for select cancers with solid tumors that test positive for a protein called Claudin 6 (CLDN6).

Compensation: No
Oncology
Skin, Hair and Nails

Collection of samples will allow for increased and more focused research on skin conditions and perhaps eventually lead to the development of improved treatment outcomes.

Compensation: No
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find the most safe and effective dose of an experimental drug called BMS-986460 (the study drug) for men with metastatic castration resistant prostate cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called ruxolitinib is a safe and effection option for preventing graft-versus-host disease when it is given in combination with the drugs tacrolimus and methotrexate before and after a peripheral blood stem cell transplant. We want to know if this study drug combination works better than the standard post-transplant treatment of cyclophosphamide, tacrolimus, and mycophenolate mofetil.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if patients with SAA who have not received previous treatment for this diagnosis can be treated safely and effectively with transplant as their first therapy.

Compensation: No
Ages: 3-75
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to see if a pair of experimental drugs called botensilimab and balstilimab are safe and effective options for colorectal cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We created this healthy volunteer registry for people who would like to participate in brain imaging research studies. These studies use structural and functional MRI data to study areas of the brain associated with movement, memory, attention, and perception.

Compensation: Yes
Ages: 18-80
Non-Oncology
Duke University Hospital