Clinical Trials Directory

436 clinical trials found.
Genitourinary Cancer

We are doing this study to find out if an experimental drug called Actinium-225 rosopatamab tetraxetan (the study drug) is a safe and effective option for patients with castration-resistant prostate cancer (CRPC).

Compensation: No
Ages: 0-64
Oncology
Duke University Hospital
Breast Cancer

We are doing this study to see whether programs are helpful for couples where one partner has cancer.

Compensation: Yes
Ages: 18-80
Oncology
Remote/online
Breast Cancer

We are doing this study to find out if an experimental drug called CRB-601 (the study drug) is a safe and effective option for people who have cancers with advanced solid tumors that did not improve with standard treatment.

Compensation: No
Ages: 18-64
Oncology
Duke University Hospital
Breast Cancer

We are doing this study to better understand how breast cancer treatment can affect the heart. In particular, we want to know if treatment with near complete estrogen deprivation (NCED) therapy has an impact on heart function.

Compensation: Yes
Ages: 18-55
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Gynecologic Cancer

We are doing this study to find out if using ice with or without compression during chemotherapy can prevent neuropathy for patients being treated for gynecologic cancer.

Compensation: No
Ages: 19-110
Oncology
Duke University Hospital, Duke Raleigh Hospital

We are doing this study to collect cerebrospinal fluid (CSF) samples from people with cancer that has spread to the leptomeninges (the inner membranes that cover the brain and spinal cord). These CSF samples will be used in laboratory research projects to identify substances called biomarkers. Biomarker testing is a way to look for genes, proteins, and other substances (tumor markers) that can provide information about cancer. Information from these CSF samples may help us learn about new methods to treat metastatic disease to the leptomeninges.

Compensation: No
Ages: 18-110
Duke University Hospital
Genitourinary Cancer

We are doing this study learn more about circulating immune cells and circulating tumor cells (CTCs) in patients with metastatic renal cell carcinoma or metastatic urothelial carcinoma. We are also looking at the bacteria in your gut and urinary tract to learn about how these bacteria affect how your cancer responds to immunotherapy.

Compensation: No
Oncology
Lungs and Breathing

We are doing this study to find out if an investigational drug called tocilizumab (the study drug) will lead to better outcomes after lung transplantation when it is combined with standard anti-rejection medicines.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital