Clinical Trials Directory

436 clinical trials found.
Breast Cancer

We are doing this study to learn more about the use of the da Vinci Single-Port Surgical System in nipple-sparing mastectomy (NSM) procedures. We want to find out if the outcomes of NSM using this robotic-assisted technology are better than the current standard of open surgery.

Compensation: Yes
Ages: 21-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to collect information about how well dabrafenib plus trametinib works in patients who have unresectable (cannot be removed by surgery) or metastatic BRAF V600E mutation positive solid tumors.

Compensation: No
Oncology
Skin Cancer - Melanoma

We are doing this study to find out if the combination of the drugs Dapansutrile and Pembrolizumab is a safe and effective treatment for people with melanoma that does not improve after PD-1 therapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Biobank / Biospecimen Collections

We are doing this study to collect and store information and samples that will be used for future research studies about transplants.

Compensation: No
Ages: 0-100
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to collect and store your medical information and specimens for use in future research studies to understand heart function and disease.

Compensation: No
Non-Oncology
Mental Health, Behavior, and Substance Abuse

We are doing this study to find out how well an emotion regulation skills training program can help expecting mothers lower stress during pregnancy and improve their heart rate.

Compensation: Yes
Ages: 18-45
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called vimseltinib (the study drug) is a safe and effective option for people with active Chronic Graft Versus Host Disease (cGVHD).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Infectious Diseases

If you choose to join this study, you will complete up to 10 study visits and 2 phone call check-ins over 72 weeks. This study includes:

  • Pulmonary function tests (how well your lungs are working)
  • CT scans of the chest (a special type of imaging that creates 3D X-ray images)
  • Blood draws
  • Questionnaires
During the study, you will be randomized (like flipping a coin) to get either:
  • The study drug (Doxycycline) by mouth twice a day for 72 weeks; OR
  • A placebo (sugar pill) by mouth twice a day for 72 weeks
  • Compensation: Yes
    Ages: 30-110
    Non-Oncology
    Duke University Hospital