Clinical Trials Directory

444 clinical trials found.
Heart and Circulation

We are doing this study to collect and store your medical information and specimens for use in future research studies to understand heart function and disease.

Compensation: No
Non-Oncology
Heart and Circulation

We are doing this study to find out if an experimental drug called ALXN2220 (the study drug) is a safe and effective option for people with transthyretin amyloid cardiomyopathy (ATTR-CM). The study drug is designed to act as a "depleter," which means its desired function is to target the active removal of pre-existing amyloids and restore the heart's function and elasticity.

Compensation: Yes
Ages: 18-90
Non-Oncology
Duke University Hospital
Infectious Diseases

If you choose to join this study, you will complete up to 10 study visits and 2 phone call check-ins over 72 weeks. This study includes:

  • Pulmonary function tests (how well your lungs are working)
  • CT scans of the chest (a special type of imaging that creates 3D X-ray images)
  • Blood draws
  • Questionnaires
During the study, you will be randomized (like flipping a coin) to get either:
  • The study drug (Doxycycline) by mouth twice a day for 72 weeks; OR
  • A placebo (sugar pill) by mouth twice a day for 72 weeks
  • Compensation: Yes
    Ages: 30-110
    Non-Oncology
    Duke University Hospital
    Research for Children and Teenagers

    We are building a database of people who would like to be contacted about future dermatology research studies. This is a way for people who are interested in participating in research opportunities to learn about a research study that they may not have otherwise known about.

    Compensation: No
    Ages: 0-110
    Non-Oncology
    Remote/online
    Eyes and Vision

    We are doing this study to find out if an experimental drug called DF-003 is a safe and effective option for people with ROSAH Syndrome.

    Compensation: No
    Ages: 18-65
    Non-Oncology
    Duke University Hospital
    Primary Brain and Spinal Cord Tumors

    We are doing this study to test the safety and effectiveness of the study drug, datopotamab deruxtecan (also known as dato-DXd), and find out if it is a potential option for patients with metastatic breast cancer that has spread to the brain and/or spinal cord.

    Compensation: No
    Ages: 18-110
    Oncology
    Duke University Hospital, Duke Raleigh Hospital
    Immunology and Rheumatology

    We are doing this study to find out if an experimental drug called CABA-201 (the study drug) is a safe and effective option for people with systemic sclerosis.

    Compensation: Yes
    Ages: 18-75
    Non-Oncology
    Duke University Hospital
    Eyes and Vision

    We are doing this study to find out if an experimental drug called tinlarebant is a safe and effective option for people with Stargardt Disease.

    Compensation: No
    Ages: 12-20
    Non-Oncology
    Duke University Hospital