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438 clinical trials found.
Brain, Spinal Cord and Nerves

We are doing this study to find out if an experimental cell therapy called NRTX-1001 (the study drug) is a safe and effective treatment for drug-resistant mesial temporal lobe epilepsy (MTLE). We want to know if the study drug can reduce seizures in people who are not getting relief from conventional treatments.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called cema-cel is a safe and effective option for patients with large B-cell lymphoma. Cema-cel is a CAR T Cell therapy that is made from your own white blood cells. We also want to compare how well cema-cel works when it is given with and without another experimental drug called ALLO-647.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Remote

We are doing this study to learn more about the needs and challenges of Black parents and caregivers who are taking care of children who have special healthcare needs. We want to be able to provide better support for these families in the future.

Compensation: Yes
Ages: 18-110
Non-Oncology
Remote/online
Diabetes Mellitus

We are doing this study to test a new intervention for people with type 1 diabetes who also have disordered eating. We hope the strategy we are testing in this study can improve diabetes management and decrease eating disorder symptoms and emotional distress.

Compensation: Yes
Ages: 16-50
Non-Oncology
Other
Heart and Circulation

We are doing this study to learn more about children with tricuspid atresia. We hope to improve care for patients with this condition in the future.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital
Women's Health

We created this registry to have database of people who are interested in participating in research about chronic pain.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to find out if an experimental drug called EDG-7500 (the study drug) is a safe and effective option for patients with both obstructive and non-obstructive hypertrophic cardiomyopathy (HCM). The study drug is designed to help the heart's ability to relax by making contractions more controlled, and we want to know how successful the drug is in achieving its intended outcome.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital, Other
Research for Children and Teenagers

We are doing this study to improve care for people with cleft lip and/or cleft palate.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital