Clinical Trials Directory

475 clinical trials found.
Eyes and Vision

We are doing this study to find out is an experimental drug called RGX-314 can help improve or preserve vision. We will compare how this drug works to Eylea®, which is an approved therapy for age-related macular degeneration.

Compensation: Yes
Ages: 50-89
Non-Oncology
Duke University Hospital
Bones, Joints and Muscles

We are doing this study to understand how different factors, such as pain experiences and inflammation, may affect how acute back pain transitions to chronic back pain.

Compensation: Yes
Ages: 18-110
Non-Oncology
Kannapolis, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called iadademstat (the study drug). We want to know if the study drug is beneficial for people with R/R AML that have the FLT3 mutation when it is given in combination with gilteritinib.

Compensation: No
Oncology

You will get your own blood pressure monitor to use at home. We will teach you how to use it. You will check your blood pressure at home and share the numbers with your doctor's team for 12 months. The research team will also collect information in other ways, like: Visits in person, Phone calls, Your medical records, Medicare data

Compensation: Yes
Ages: 65-110
Other

This study needs two overnight stays to give a special medicine called choline and to make sure it is safe. It also includes ten visits to the clinic over about sixteen months.

Compensation: Yes
Ages: 12-110
Duke University Hospital
Genitourinary Cancer

Compensation: No
Oncology
Heart and Circulation

We are doing this to compare the results of early surgical intervention to medical therapy. We want to know if there is a difference in outcomes for these treatment options. We also want to track the health and progress of people with a large ascending aortic aneurysm (a bulge in the aorta caused by weakening in the artery wall).

Compensation: No
Non-Oncology
Gynecologic Cancer

We are doing this study to find out if an experimental drug called TORL-1-23 (the study drug) is a safe and effective option for women who have advanced ovarian cancer, primary peritoneal, or fallopian tube cancer.

Compensation: No
Ages: 18-110
Oncology
Duke Raleigh Hospital