Clinical Trials Directory

436 clinical trials found.
Breast Cancer

We are doing this study to try and find a way to detect breast cancer earlier or before it recurs.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out if an experimental drug called zifibancimig (the study drug) is a safe and effective option for people with neovascular age-related macular degeneration (nAMD). We want to see how well it works in comparison to ranibizumab, which is an FDA-approved drug for the treatment of nAMD. Both the study drug and approved drug that are used in this study are given as eye implants.

Compensation: Yes
Ages: 55-89
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to compare different approaches aimed at preventing strokes for people who have already had a stroke. We want to know what combination of drugs seems to have the best outcomes when it comes to stroke prevention.

Compensation: Yes
Ages: 30-49
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to find out if an experimental drug called eplontersen (the study drug) is safe and helpful for people with cardiac amyloidosis. We are enrolling people who previously participated in a clinical trial for this drug called the CardioTTRansform study (ION-682884-CS2).

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called AS 1763 (the study drug) is a safe and effective option patients with B-cell cancers. We also want to know what the maximum, safe dose of the study drug is.

Compensation: Yes
Ages: 0-64
Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to see how different things, like medical and treatment history, affect outcomes in people with cardiac amyloidosis.

Compensation: No
Non-Oncology
Thoracic Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called visugromab (CTL-002 - the study drug). We want to find out how beneficial this drug is when it is used in combination with immunochemotherapy for people with metastatic non-squamous non-small cell lung cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called CAP-100 (study drug) is a safe and effective treatment for people who have CLL or SLL that is not responding to standard treatments. We also want to know what dose of this study drug works best.

Compensation: No
Oncology