Clinical Trials Directory

488 clinical trials found.
Brain, Spinal Cord and Nerves

Compensation: No
Non-Oncology
Gastrointestinal Cancer

In this study, you will take a medicine called ALTA3263 by mouth every day. You will keep taking it until your cancer gets worse or until you need to stop because of strong or frequent side effects. While you are in the study, you will go to the clinic for regular visits. During these visits, the study team will do tests to check your health and collect information for research.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Kidneys, Bladder and Urinary System

We are doing this study to find out if an experimental drug called ALXN2030 (the study drug) is a safe and effective option for people diagnosed with antibody-mediated rejection (AMR) of a transplanted kidney.

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.

Compensation: No
Oncology
Gastroenterology

We are doing this study to learn more about how androgens, a type of sex hormone, might affect women who have nonalcoholic fatty liver disease (NAFLD). We want to see if they play a role in how the disease effects women over time, and we also want to see what role these hormones might play in the relationship between NAFLD and polycystic ovary syndrome.

Compensation: Yes
Ages: 18-42
Non-Oncology
Duke University Hospital
Skin Cancer - Melanoma

We are doing this study to find the most effective, safe dose of a combination of the drugs fianlimab and ceminplimab. We want to know if this combination is an option for people with melanoma. We will compare how well this drug combination works to the usual treatment of relatlimab and nivolumab, which has the brand name Opdualag®.

Compensation: No
Ages: 18-85
Oncology
Duke Raleigh Hospital