Clinical Trials Directory

We are doing this study to find out if a medical technology called the Signatera blood test can help doctors and patients determine the best course of treatment for bladder cancer after the patient has a radical cystectomy (removal of the bladder and surrounding lymph nodes). The Signatera test is used to detect cancer DNA in the blood before cancer can be seen using imaging (like MRI or CT scans).

We are doing this study to find out if an investigational gene therapy drug called ABBV-RGX-314 (the study drug) is a safe and effective option for people with diabetic retinopathy. The study drug is delivered directly into the suprachoroidal space of the eye using a technology called Microinjector®, which is an experimental needle device.

We are doing this study to find out if an experimental test for the detection of hepatocellular carcinoma (liver cancer) called Oncoguard® is a reliable and accurate means to detect the disease in its earliest stages.

We are doing this study to find out if an experimental drug called AMG 355 (the study drug) is a safe and effective option for people who have a solid tumor form of cancer that is metastatic (spread to surrounding tissues in the body). We want to know how well the study drug works on its own or in combination with an approved cancer drug called pembrolizumab.

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells. The first part of this study will test different doses of AMG-509 in men to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth. This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

We are doing this study to find the most effective, safe dose of an experimental drug called xaluritamig (the study drug). We want to know how well this drug works compared to the standard drugs for people who have metastatic castration-resistant prostate cancer.

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.