Clinical Trials Directory

473 clinical trials found.
Transplant Medicine

We are doing this study to find out if an experimental drug called ALXN2030 (the study drug) is a safe and effective option for people diagnosed with antibody-mediated rejection (AMR) of a transplanted kidney.

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to find out if an experimental drug called tarlatamab (the study drug) is a safe and effective option for people who have small cell lung cancer (SCLC) that has progressed and spread to other parts of the body.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called xaluritamig (the study drug). We want to know how well this drug works compared to the standard drugs for people who have metastatic castration-resistant prostate cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Brain and Spine Metastasis

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.

Compensation: No
Oncology
Digestive System

We are doing this study to learn more about how androgens, a type of sex hormone, might affect women who have nonalcoholic fatty liver disease (NAFLD). We want to see if they play a role in how the disease effects women over time, and we also want to see what role these hormones might play in the relationship between NAFLD and polycystic ovary syndrome.

Compensation: Yes
Ages: 18-42
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called APL-5125 (the study drug) is a safe and effective for people with select types of gastrointestinal cancer. We are also trying to find the best dose of APL-5125 to use.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Transplant Medicine

We are doing this study to see if people have the L1 gene called apolipoprotein (APOL1) and to learn how this may affect them.

Compensation: No
Non-Oncology