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436 clinical trials found.
Skin, Hair and Nails

We are doing this study to find out if an experimental drug called brepocitinib (the study drug) is a safe and effective option for people with cutaneous sarcoidosis.

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Phase I

We are doing this study to find out if an experimental drug called BGB-43395 (the study drug) is a safe and effective option for people with for breast cancer and other advanced solid tumors. We want to know how the study drug works on its own and in combination with other cancer drugs.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most safe and effective long-term dose of an experimental drug called zanubrutinib (the study drug) when it is given alone or in combination with other cancer drugs. We want to know how well this study drug works in people with B-cell cancers who are currently participating or previously participated in a BeiGene-sponsored study.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to monitor the health of the cornea in participants with neovascular age-related macular degeneration (nAMD), also know as wet AMD, who receive an eye implant that continuously delivers the drug ranibizumab into the back of the eye.

Compensation: Yes
Ages: 55-89
Non-Oncology
Duke University Hospital
Head and Neck Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called ficerafusp alfa (BCA101 - the study drug) when it is given in combination with pembrolizumab for people who have metastatic/recurrent head and neck squamous cell carcinoma (HNSCC).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Endocrine and Metabolic System

We are doing this study to find out if an experimental drug called pegozafermin (the study drug) is a safe and effective option for people who have compensated liver cirrhosis due to MASH.

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to collect data, liquid biopsies (blood and urine), and cancer specimens from women with primary epithelial ovarian, peritoneal, or tubal cancer. We are using this information and these samples to create a biobank that might identify future therapeutic targets and help develop new therapies for these types of cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Bones, Joints and Muscles

We are doing this study to test if an experimental medical device called the Bioenthesis® implant (the study device) is a safe and effective option for people who are having surgery to repair a torn rotator cuff. The study device is a bubble gum strip-sized, sponge-like scaffold that is made of real human tissue. The implant has two layers: a soft tissue layer to merge with your tendon, and a hard tissue layer to allow a patient's own stem cells to populate the implant from the bone marrow.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital