Clinical Trials Directory

401 clinical trials found.
Cancer Prevention and Screening

We are doing this study to improve how patients and their primary care providers can keep up with routine health maintenance during cancer treatments. We want to know if a new model of communication between patients and their doctors can improve health outcomes.

Compensation: Yes
Ages: 18-59
Oncology
Remote/online
Brain, Spinal Cord and Nerves

We are doing this study to compare activity in the brains of female adults who have chronic pain and/or use opioids to the brain activity of healthy female adults who are pain-free. We hope this study can help us develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called linvoseltamab (the study drug) compared to a combination of three cancer drugs(elotuzumab, pomalidomide, and dexamethasone) for people who have multiple myeloma.

Compensation: No
Oncology
Thoracic Cancer

We are doing this study to find out if an experimental drug called ORIC-114 (the study drug) is a safe and effective option for possible treatment in patients with advanced solid tumors harboring an EGFR or HER2 alteration.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out if an experimental drug called axitinib (the study drug) is a safe and effective option for people with neovascular age-related macular degeneration (nAMD). The study drug is given to people using a developing technology called the Ocular Therapeutix Intravitreal Implant (OTX-TKI).

Compensation: Yes
Ages: 55-89
Non-Oncology
Duke University Hospital
Blood Disorders

We are doing this study to learn more about the effects of the prescription drug Oxbryta (voxelotor) on sickle cell disease (SCD) when it is prescribed to patients. We want to keep track of the health of people with SCD who take this drug as part of their normal care.

Compensation: Yes
Ages: 12-110
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study is to collect additional follow-up data and samples from participants who completed the P-RAD clinical trial.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to evaluate the performance of an experimental medical technology called the Patched Sepsis Prediction Algorithm (the study technology). This technology is designed to detect the early signs of sepsis and give clinicians the chance to treat it earlier than usual.

Compensation: No
Oncology