Clinical Trials Directory

435 clinical trials found.
Research for Healthy Adults

We are doing this study to test an experimental simulation of "extravehicular activities" (EVAs), which are more commonly known as spacewalks. We want to know if this simulation will provide good training for astronauts who will have to perform EVAs during their space missions.

Compensation: Yes
Ages: 18-50
Non-Oncology
Duke University Hospital
COVID-19

We are doing this study to learn more about changes in nasal tissue in people that have COVID-19. Many COVID-19 patients have reported a change in sense of smell and we would like to find out why that is.

Compensation: No
Non-Oncology
Research for Children and Teenagers

We are using you or your child's medical information in this study to better understand the diagnosis, treatment, and complications of Spina Bifida.

Compensation: No
Ages: 0-110
Non-Oncology
Remote/online, Duke University Hospital
Brain, Spinal Cord and Nerves

We created the Registry for Brain Health to help you improve your brain health and get involved in research studies. The number of people in North Carolina affected by memory disorders, such as Alzheimer's disease and other forms of dementia, is going up. To change that, we must work together, stay informed, and get involved. We are enrolling both people who have memory problems and people who are healthy and do not have memory problems.

Compensation: No
Ages: 18-110
Non-Oncology
Other
Skin Cancer - Melanoma

We are doing this study to find out if an investigational called Daromun (the study drug) is a safe and effective treatment for melanoma. We want to know if treating people with the drug before surgery to remove tumors can lower the chance of cancer recurrence.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Endocrine and Metabolic System

We are doing this study to learn more about the following symptoms that can be related to primary hyperparathyroidism: confusion, difficulty remembering and focusing, memory fog, changes in a person's normal behavior, feeling "blue", increased anxiety, increased agitation, and trouble performing daily activities, like driving and remembering appointments. We want to know how much these symptoms change in older adults after they have endocrine surgery.

Compensation: No
Ages: 65-110
Non-Oncology
Duke University Hospital
Mental Health, Behavior, and Substance Abuse

We are doing this study to find out if combining psychological skills and a procedure called neurostimulation during one clinic session can help reduce negative emotions and problems with dealing with emotions in both a laboratory setting and in a person's everyday life.

Compensation: Yes
Ages: 18-55
Non-Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if an investigational drug called NMS-0330593 (the study drug) is safe and effective option when it is given in combination with temozolomide (an approved drug for the treatment of diffuse glioma). We want to know if this drug combination works better than temozolomide on its own.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital