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This study will last about two to a little over two years from the day you sign up until your last checkup. If the doctors decide you are a good fit after the first tests, you will have surgery to place the ARCIM System inside your body. After the surgery, you will have many checkups over the next two years so the study team can see how well the treatment is working for you. During these visits, the team will adjust the device to make sure it works well for your daily life. You will also answer questions and take part in health checkups during clinic visits. Some visits will be done by email or phone. Altogether, you will spend about fifteen days in person at the clinic during the whole study. The study team will be there to help and guide you at every step.

We are doing this study to learn more about how brain cell activity guides memory and navigation.

The Endometrial Cancer Molecularly Targeted Therapy Consortium is a multi-institutional alliance that is developing a cancer data and tissue repository. The information in this repository will be used to better understand tumor alterations and cancer biomarkers that can help us develop new therapies and potentially improve survival outcomes for women with endometrial cancer.

In this study, people will get a special shot called a nerve block. It is given in the back of the neck while the person is asleep under general anesthesia. This means they will not feel anything during the procedure.

We are doing this study to keep tabs on the performance of a medical device called TVT Exact. This device is used to help control stress urinary incontinence. We want to know how well this device works long-term in Duke patients who elected to use it.