Directorio

We are doing this study to find the most effective, safe dose of an experimental drug called selinexor (the study drug) for people with myelofibrosis (MF).

We are doing this study to compare a ketogenic diet (a diet with high fat, moderate protein, very low carbohydrate) versus a normal diet. We want to find out if it has any effect on survival time for people with glioblastoma multiforme (GBM). We also want to know how biomarkers change when people follow a ketogenic diet. A biomarker is a biological molecule found in blood, other body fluids, or tissues. Biomarkers may be a sign of a condition or disease and can be used to predict someone's response to a specific treatment.

We are doing this study to learn more about what causes glioblastoma (GBM), a type of brain cancer, and the factors that affect GBM patients' quality of life. This research will help us to understand why some people get GBM, including how their genes and health history may contribute to tumor development and progression.

This is a research study to see if two doses (low and high) of the KPI-012 eye drops are safe and work to repair persistent corneal epithelial defects (PCED), a non-healing corneal wound that does not heal with standard treatments, compared to the placebo (eye drops without any active ingredients).

We are doing this study to find the most effective, safe dose of an experimental drug called ziftomenib (the study drug). We want to know how well this study drug works in people with AML that have certain mutations in the NPM1 gene and rearrangements involving the KMT2A gene when it is given alone or in combination with other cancer drugs.

We are doing this study to find the most effective, safe dose of an experimental drug called ziftomenib (the study drug) to be used in combination with an established dose of imatinib for people who have advanced gastrointestinal stromal tumors (GIST) and failed treatment with imatinib on its own.

We are doing this study to compare 2 different surgeries for epithelial ovarian cancer. We want to know if an investigational surgical procedure called minimally invasive surgery can offer better results than the standard surgery, which is called laparotomy. We hope to find out if one procedure or the other is preferable when it comes to preventing cancer from returning and giving patients a better quality of life after their surgery.

We are doing this study to find out how changes in air pressure can affect people's exercise capacity. We want to compare how these pressure changes affect the abilities of healthy volunteers and compare their changes to those of people who are diagnosed with HFpEF (heart failure with a preserved ejection fraction, a congestive heart disease).