Clinical Trials Directory

276 clinical trials found.
Thoracic Cancer

We are doing this study to research the genes of patients with lung cancer that has been or will be removed by surgery for a chance to get treatment in a clinical trial.

Compensation: No
Oncology
Brain and Spine Metastasis

We are doing this study to compare the usual treatment alone (treatment with ipilimumab and nivolumab followed by nivolumab alone) to the usual treatment with ipilimumab and nivolumab, follwed by nivolumab and cabozantinib.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to measure the effect of different dosages of Danicopan (the study drug) on the progression of GA secondary to AMD compared to a placebo.

Compensation: No
Non-Oncology
Brain and Spine Metastasis

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells.

The first part of this study will test different doses of AMG-509 in men, to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth.

This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out how an experimental drug called sotorasib works in your body and against your cancer. We will compare how this drug works alone and in combination with several different drugs.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to collect symptom and treatment experience data from patients with acute myelogenous leukemia (AML) being seen at the Duke Cancer Institute. We will add this data to a data registry and use it to identify quality improvement opportunities.

Compensation: No
Ages: 18-89
Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about adults and children with anomalous aortic origin of coronary arteries. We hope to improve care for patients with this condition in the future.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital
Ear, Nose and Throat

We are doing this study to find out if it is necessary to treat people with antibiotics after nasal surgery. We want to know if antibiotics are helpful or not during the healing process after surgery.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital