Clinical Trials Directory

434 clinical trials found.
Older Adults/Aging

We are doing this study to learn more about Alzheimer's disease and other illnesses of aging (e.g., dementia, mild cognitive impairment [MCI], or other cognition disorders).

Compensation: Yes
Ages: 25-80
Non-Oncology
Duke University Hospital
Lungs and Breathing

We are doing this study to find out if L-citrulline (the study drug) will help improve asthma symptoms when taken daily. This study is important because managing symptoms of asthma can improve quality of life and long-term health.

Compensation: Yes
Ages: 18-65
Non-Oncology
Other
Mental Health, Behavior, and Substance Abuse

We are doing this study to learn more about sleep and body rhythms in children with ADHD. We will use home-based measures, parent reports, and an evening test to see how sleep affects mental health and thinking skills. Dr. Jessica Lunsford-Avery from the Department of Psychiatry is leading this study.

Compensation: Yes
Ages: 6-9
Non-Oncology
Other
Eyes and Vision

We are doing this study to find out if an experimental drug called ADX-2191 (the study drug) is a safe and effective option for people with retinitis pigmentosa (RP) due to confirmed rhodopsin mutations.

Compensation: Yes
Ages: 21-110
Non-Oncology
Duke University Hospital
Gynecologic Cancer

We are doing this study to find out if certain experimental drug combinations are safe and effective options for people who have recurrent or persistent endometrial cancer (cancer that has come back after treatment or does not respond to treatment).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Pediatric Cancer

We are doing this study to find out if carefully watching patients with low risk germ cell tumors after surgery will have different results than treating people with chemotherapy afer their surgery. For people who are in standard risk groups related to germ cell tumors, we want to compare the effects of carboplatin with cisplatin and find out which of these drugs seems to work better.

Compensation: No
Oncology
Digestive System

We are doing this study to find out if an experimental drug called efruxifermin (EFX) is a safe and effective option for people who have nonalcoholic steatohepatitis (NASH)/metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis (scarring of the liver tissue).

Compensation: Yes
Ages: 18-80
Non-Oncology
Duke University Hospital
Older Adults/Aging

We are doing this study to help us identify the underlying causes of brain disorders such as delirium and/or dementia.

Compensation: Yes
Ages: 60-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital