Clinical Trials Directory

428 clinical trials found.
Older Adults/Aging

We are doing this study is to test the effectiveness of a new virtual exercise training program created for older individuals who are living with prediabetes.

Compensation: Yes
Ages: 60-110
Non-Oncology
Duke University Hospital, Other
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if an experimental drug combination of vorasidenib and temozolomide (the study drugs) is a safe and effective option for people who have glioma with IDH1 or IDH2 mutations.

Compensation: No
Ages: 12-110
Oncology
Duke University Hospital
Heart and Circulation

We are doing this study is to see if we can predict carotid artery function using wearable technology (for example, a FitBit®).

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study to find out if an experimental drug and device system called X-PACT is a safe and effective treatment for various forms of cancer.

Compensation: Yes
Ages: 8-110
Oncology
Duke University Hospital, Other
Genitourinary Cancer

We are doing this study to find out if an experimental drug called XmAb819 (the study drug) is a safe and effective treatment for clear cell renal cell carcinoma (ccRCC).

Compensation: No
Oncology
Lungs and Breathing

We are doing this study to learn how to get the best quality images of lungs in an MRI scanner as people breathe in Xenon gas. We hope this imaging will show key differences between diseased and healthy lungs.

Compensation: Yes
Ages: 18-90
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called XTX101 (the study drug) is a safe and effective option for people who have advanced tumors or metastatic microsatellite stable colorectal cancer. We want to see how well it works on its own and in combination with a drug called atezolizumab.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to find out if Non-Ischemic Heart Preservation using an experimental technology called the XVIVO Heart Preservation System (the study technology) is a safe and effective way to preserve extended criteria donor hearts that can be transplanted into patients who need a donor heart. The study technology is designed to preserve donor hearts using a device with a temperature-controlled perfusion solution that flows through the heart during transport. We want to know if this can allow donor hearts to travel a greater distance to patients who are awaiting a transplant.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital