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436 clinical trials found.
Eyes and Vision

We are doing this study to find out is an experimental drug called RGX-314 can help improve or preserve vision. We will compare how this drug works to Eylea®, which is an approved therapy for age-related macular degeneration.

Compensation: Yes
Ages: 50-89
Non-Oncology
Duke University Hospital
Bones, Joints and Muscles

We are doing this study to understand how different factors, such as pain experiences and inflammation, may affect how acute back pain transitions to chronic back pain.

Compensation: Yes
Ages: 18-110
Non-Oncology
Kannapolis, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called iadademstat (the study drug). We want to know if the study drug is beneficial for people with R/R AML that have the FLT3 mutation when it is given in combination with gilteritinib.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to find out if an investigational implanted drug called Ocular Therapeutix Tyrosine Kinase Inhibitor Axitinib (the study drug) is a safe and effective option for people with nAMD.

Compensation: Yes
Ages: 50-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about the effects of exercise and medication on symptoms of worry and stress in adults with heart disease. This study is important because symptoms of worry and stress are risk factors for worsening heart health.

Compensation: No
Non-Oncology
Genitourinary Cancer

Compensation: No
Oncology
Heart and Circulation

We are doing this to compare the results of early surgical intervention to medical therapy. We want to know if there is a difference in outcomes for these treatment options. We also want to track the health and progress of people with a large ascending aortic aneurysm (a bulge in the aorta caused by weakening in the artery wall).

Compensation: No
Non-Oncology
Thoracic Cancer

We are doing this study to find out if 2 investigational drugs called aliocumab and cemiplimab (the study drugs) are a safe and effective option to treat NSCLC that has spread to other organs in the body and help patients live disease free for a longer period of time.

Compensation: No
Oncology