Clinical Trials Directory

276 clinical trials found.
Thoracic Cancer

We are doing this study to see if combining immunotherapy with chemotherapy is a better treatment than chemotherapy alone for NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Thoracic Cancer

We are doing this study to find out if adding a procedure called stereotactic body radiation therapy (SBRT) to the standard treatment for advanced NSCLC can improve outcomes for patients with this type of cancer.

Compensation: No
Oncology
Thoracic Cancer

We are doing this study to compare the usual treatment of Nivolumab and ipilimumab to using the usual treatment plus surgery for people with sarcomatoid mesothelioma. We want to find out if adding surgery to the immunotherapy regimen is effective in stabilizing this type of cancer.

Compensation: No
Oncology
Heart and Circulation

We are doing this to learn more about the safety and performance of the Abbott annuloplasty rings in treating heart valve disease.

Compensation: No
Non-Oncology
Brain and Spine Metastasis

We are doing this study to find the best dose of the study drug, ABBV-400, and to see if it is a safe and effective option for treating cancer.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating various types of solid tumors.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called ABBV-453 (the study drug) is a safe and effective treatment for multiple myeloma. We want to identify the most appropriate dose and schedule to give patients the study drug.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental study drug called venetoclax (Venclexta) is a safe and effective treatment for relapsed or refractory multiple myeloma. We want to see if people have better outcomes when they're treated with the study drug and standard drugs, carfilzomib (Kyprolis) and dexamethasone, versus just the standard drugs on their own.

Compensation: No
Oncology