Clinical Trials Directory

We are doing this study to test a new strategy to help people quit smoking. We want to know if the study approach is better than the usual approach. The usual approach is to encourage patients to quit smoking using cessation support manuals and either medication or nicotine replacement products. We want to know if the study approach works better for cancer survivors who live in rural areas.

We are doing this study to find out if an experimental gene therapy drug called ABBV-RGX-314 (the study drug) has similar effects to approved drugs, such as Lucentis® or Eylea® injections. The study drug will be injected into one eye with a Suprachoroidal Space (SCS) Microinjector®, which is an investigational needle device developed by Clearside Biomedical, Inc.

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating colorectal cancer when it is combined with the following standard-of-care drugs: 5-fluorouracil, folinic acid, and bevacizumab. We are also trying to find the best dose and frequency of ABBV-400 to use.

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating various types of solid tumors.

We are doing this study to understand if the abdominal wall transplant can repair defects in the abdominal wall.

We are doing this study to collect information about people with oligometastasis for future use.

We are doing this study to compare measures of brain function after surgical circulatory arrest ( when the surgeon stops the heart-lung machine to work on your heart) in antegrade perfusion versus retrograde perfusion. Antegrade and retrograde perfusion are 2 different ways to supply blood to the brain during this type of surgery. In antegrade perfusion, the surgeon accesses one of two arteries that branch off from the aorta (the artery that delivers blood to the rest of the body) to provide blood to the brain. In retrograde perfusion, the surgeon accesses the superior vena cava (large vein bringing blood back to the heart) to supply blood to the brain. Both methods are commonly used, but we want to find out if one method works better for most people than the other.

We are doing this study to compare 2 different versions of a balance test. We want both people who have had an anterior cruciate ligament (ACL) procedure and people with no history of ligament injury to do these tests. We hope this study can help us develop better testing methods to figure out when it is appropriate for people to return to their regular activities after an ACL procedure.