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403 clinical trials found.
Gynecologic Cancer

We are doing this study to find out if certain experimental drug combinations are safe and effective options for people who have recurrent or persistent endometrial cancer (cancer that has come back after treatment or does not respond to treatment).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Pediatric Cancer

We are doing this study to find out if carefully watching patients with low risk germ cell tumors after surgery will have different results than treating people with chemotherapy afer their surgery. For people who are in standard risk groups related to germ cell tumors, we want to compare the effects of carboplatin with cisplatin and find out which of these drugs seems to work better.

Compensation: No
Oncology
Older Adults/Aging

We are doing this study to help us identify the underlying causes of brain disorders such as delirium and/or dementia.

Compensation: Yes
Ages: 65-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Brain and Spine Metastasis

We are doing this study to find out if a new experimental drug called NVL-655 (the study drug) is a beneficial option for people with NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to learn more about the side effects of the study drug and to determine if it will help shrink the cancer by at least 30%.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to research the genes of patients with lung cancer that has been or will be removed by surgery for a chance to get treatment in a clinical trial.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Eyes and Vision

We are doing this study to find out if an investigational gene therapy drug called ABBV-RGX-314 (the study drug) is a safe and effective option for people with diabetic retinopathy. The study drug is delivered directly into the suprachoroidal space of the eye using a technology called Microinjector®, which is an experimental needle device.

Compensation: Yes
Ages: 25-89
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells. The first part of this study will test different doses of AMG-509 in men to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth. This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital