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We are using you or your child's medical information in this study to better understand the diagnosis, treatment, and complications of Spina Bifida.

We created the Registry for Brain Health to help you improve your brain health and get involved in research studies. The number of people in North Carolina affected by memory disorders, such as Alzheimer's disease and other forms of dementia, is going up. To change that, we must work together, stay informed, and get involved. We are enrolling both people who have memory problems and people who are healthy and do not have memory problems.

We are doing this study to learn more about the rare diagnosis of New Daily Persistent Headache (NDPH). We want to get more information about why some children and young people develop this condition and how it is different from traditional headaches, like migraines. This knowledge can help us to begin developing possible treatments for NDPH.

We are doing this study to find out if an investigational called Daromun (the study drug) is a safe and effective treatment for melanoma. We want to know if treating people with the drug before surgery to remove tumors can lower the chance of cancer recurrence.

We are doing this study to find out if an experimental drug called NT-I7 is a safe and effective treatment for people with LBL. The study drug will be combined with Kymriah, which is an approved, standard treatment for LBL.

We are doing this study to learn more about the following symptoms that can be related to primary hyperparathyroidism: confusion, difficulty remembering and focusing, memory fog, changes in a person's normal behavior, feeling "blue", increased anxiety, increased agitation, and trouble performing daily activities, like driving and remembering appointments. We want to know how much these symptoms change in older adults after they have endocrine surgery.

We are doing this study to find out if combining psychological skills and a procedure called neurostimulation during one clinic session can help reduce negative emotions and problems with dealing with emotions in both a laboratory setting and in a person's everyday life.

We are doing this study to compare different treatment options for people who have surgery to remove melanoma. We want to know if it is better to treat people with nivolumab alone after surgery, or if it is better to give people a combination of nivolumab and ipilimumab.