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445 clinical trials found.
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ABBV-400 (the study drug) is a safe and effective option for treating various types of solid tumors.

Compensation: No
Oncology
Surgery and Rehabilitation

We are doing this study to understand if the abdominal wall transplant can repair defects in the abdominal wall.

Compensation: No
Ages: 18-65
Non-Oncology
Duke University Hospital
Cancer Immunotherapy

We are doing this study to find out if the combination of 2 experimental drugs called C-TIL051 and NKTR-255 when they are given along with pembrolizumab is a safe and effective option for non-small cell lung cancer (NSCLC). C-TIL051 is custom-made for each participant from their own tumor tissue. Immune cells are isolated from your tumor tissue, regrown in a lab, and then formulated to be returned to your bloodstream. We want to know if C-TIL051 can help people's immune systems target and destroy cancer cells. NKTR-255 is designed to help C-TIL051 work better.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Radiation Oncology

We are doing this study to collect information about people with oligometastasis for future use.

Compensation: No
Ages: 18-110
Oncology
Remote/online
Bones, Joints and Muscles

We are doing this study to compare 2 different versions of a balance test. We want both people who have had an anterior cruciate ligament (ACL) procedure and people with no history of ligament injury to do these tests. We hope this study can help us develop better testing methods to figure out when it is appropriate for people to return to their regular activities after an ACL procedure.

Compensation: No
Ages: 18-25
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to learn more about Alzheimer's disease and other illnesses of aging (e.g., dementia, mild cognitive impairment [MCI], or other cognition disorders).

Compensation: Yes
Ages: 25-80
Non-Oncology
Duke University Hospital
Lungs and Breathing

We are doing this study to find out if L-citrulline (the study drug) will help improve asthma symptoms when taken daily. This study is important because managing symptoms of asthma can improve quality of life and long-term health.

Compensation: Yes
Ages: 18-65
Non-Oncology
Other
Mental Health, Behavior, and Substance Abuse

We are doing this study to learn more about sleep and body rhythms in children with ADHD. We will use home-based measures, parent reports, and an evening test to see how sleep affects mental health and thinking skills. Dr. Jessica Lunsford-Avery from the Department of Psychiatry is leading this study.

Compensation: Yes
Ages: 6-9
Non-Oncology
Other