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We are doing this study to test a new strategy to help people quit smoking. We want to know if the study approach is better than the usual approach. The usual approach is to encourage patients to quit smoking using cessation support manuals and either medication or nicotine replacement products. We want to know if the study approach works better for cancer survivors who live in rural areas.

In this study, you will be placed into one of two treatment groups. One group will receive two medicines called telisotuzumab adizutecan and bevacizumab, given through a vein every three weeks. The other group will receive bevacizumab through a vein every two weeks and take a medicine called LONSURF by mouth on a repeating schedule. You will keep taking the study medicines as long as they are helping and side effects are manageable. Treatment is expected to last about one year. During treatment, you will have regular clinic visits and medical tests to check your health. After stopping the study medicines, you will have follow up visits at two weeks, one month, and about three months, and then the study team will check on you every three months to see how you are doing.

People in this study will be in one of two groups. One group will get a medicine called ABBV-400 through an IV every 21 days. The other group will not get medicine but will have blood tests for cancer DNA and imaging scans to check for cancer.

What happens in this study? - You'll get the study medicine through an IV every 3 weeks - Depending on your group, you might also get: - Budigalimab (a new medicine being tested) - Or a standard cancer medicine - You'll give blood and urine samples - You'll have regular CT or MRI scans to check your health

We are doing this study to understand if the abdominal wall transplant can repair defects in the abdominal wall.

We are doing this study to collect information about people with oligometastasis for future use.

The COMET Study includes up to 4 visits to the study center. Each visit lasts about 2 to 3 hours. During the visits, children will wear special equipment for a brain test called an EEG and do fun, play-based activities. Parents or caregivers may be asked to answer questions or do interviews at home. Families will get $50 for each visit.