Clinical Trials Directory

433 clinical trials found.

What happens in this study? - People will do a 30-minute interview by phone or Zoom - The interview will be recorded - No follow-up visits or interviews will happen after that

Compensation: Yes
Ages: 70-110
Remote/online

This study is for people with type 1 diabetes (T1D). Their immune system attacks cells in the body that make insulin. A new treatment called GNTI-122 is made from their own blood cells and may help stop this attack. People will be in one of three groups: low dose, high dose, or high dose with another medicine called rapamycin. The study includes several visits to check if the treatment works and is safe.

Compensation: Yes
Ages: 18-45
Duke University Hospital
Infectious Diseases

If you choose to join this study, you will complete up to 10 study visits and 2 phone call check-ins over 72 weeks. This study includes:

  • Pulmonary function tests (how well your lungs are working)
  • CT scans of the chest (a special type of imaging that creates 3D X-ray images)
  • Blood draws
  • Questionnaires
During the study, you will be randomized (like flipping a coin) to get either:
  • The study drug (Doxycycline) by mouth twice a day for 72 weeks; OR
  • A placebo (sugar pill) by mouth twice a day for 72 weeks
  • Compensation: Yes
    Ages: 30-110
    Non-Oncology
    Duke University Hospital
    Research for Children and Teenagers

    We are building a database of people who would like to be contacted about future dermatology research studies. This is a way for people who are interested in participating in research opportunities to learn about a research study that they may not have otherwise known about.

    Compensation: No
    Ages: 0-110
    Non-Oncology
    Remote/online
    Eyes and Vision

    We are doing this study to find out if an experimental drug called DF-003 is a safe and effective option for people with ROSAH Syndrome.

    Compensation: No
    Ages: 18-65
    Non-Oncology
    Duke University Hospital
    Breast Cancer

    We are doing this study to test the safety and effectiveness of the study drug, datopotamab deruxtecan (also known as dato-DXd), and find out if it is a potential option for patients with metastatic breast cancer that has spread to the brain and/or spinal cord.

    Compensation: No
    Ages: 18-110
    Oncology
    Duke University Hospital, Duke Raleigh Hospital
    Research for Healthy Adults

    We are doing this study to find out if an experimental vaccine called Cov-RBD-scNP-001 (the study vaccine) provides safe and effective protection against multiple different coronaviruses, including the virus that causes COVID-19. We want to know the effects of the vaccine when it's given at 3 different dose levels.

    Compensation: Yes
    Ages: 18-55
    Non-Oncology
    Other
    Brain, Spinal Cord and Nerves

    We are doing this study to find out if an investigational drug called iptacopan (the study drug) is safe and has beneficial effects for people who have generalized Myasthenia Gravis (gMG).

    Compensation: Yes
    Ages: 18-75
    Non-Oncology
    Duke University Hospital